Evaluation of the effects of new combined adsorbent on occurrence of pathological lesions in aflatoxin b1‐challenged broiler chickens
This experiment was performed to investigate the protective eff ect of a new combined adsorbent (bentonite + yeast cell wall extract) previously tested in vitro, on the occurrence of pathological lesions in broilers fed a diet contaminated with afl atoxin B1 until 21 days of age. A total of 96 one-d...
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| Format: | Article |
| Language: | English |
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Kafkas University, Faculty of Veterinary Medicine
2022-01-01
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| Series: | Kafkas Universitesi Veteriner Fakültesi Dergisi |
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| Online Access: | https://vetdergikafkas.org/pdf.php?id=2883 |
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| author | Biljana DJURDJEVIĆ Marko PAJIĆ Slobodan KNEŽEVIĆ Vladimir POLAČEK Ksenija NEŠIĆ Ivana VUČIĆEVIĆ Dušica OSTOJIĆ ANDRIĆ |
| author_facet | Biljana DJURDJEVIĆ Marko PAJIĆ Slobodan KNEŽEVIĆ Vladimir POLAČEK Ksenija NEŠIĆ Ivana VUČIĆEVIĆ Dušica OSTOJIĆ ANDRIĆ |
| author_sort | Biljana DJURDJEVIĆ |
| collection | DOAJ |
| description | This experiment was performed to investigate the protective eff ect of a new combined adsorbent (bentonite + yeast cell wall extract)
previously tested in vitro, on the occurrence of pathological lesions in broilers fed a diet contaminated with afl atoxin B1 until 21 days of age.
A total of 96 one-day old Ross 308 hybrid broiler chickens were divided into four groups: group I (control), group II (5 g/kg adsorbent), group
III (5 g/kg adsorbent + 2 mg/kg afl atoxin B1), and group IV (2 mg/kg afl atoxin B1). Grossly, AFB1 and AFB1+adsorbent fed birds showed
enlargement, friable texture of liver and enlargement and pallorness of kidneys. Spleen revealed size reduction. No gross-pathological
changes were observed in control and group II. Histopathologically, lesions were observed in afl atoxicated groups. Liver revealed vacuolar
cell degeneration, periportal and perivascular infiltration of mononuclear cells. Kidneys revealed mild to moderate degree of haemorrhages,
tubular epithelial necrosis and infiltration of mononuclear cells along with heterophils. In group IV, catarrhal enteritis characterized by
desquamation of epithelial cells were found in the duodenum. A milder form of gross and histopathological lesions was seen in group III. In
conclusion, the present study revealed that supplementation of a new combined toxin binder product in the concentration of 5 g/kg could
not completely ameliorate afl atoxicity in broilers, although it met the stringent European regulation requirements for the minimum of 90%
afl atoxin binding efficiency in in vitro study. |
| first_indexed | 2024-03-13T04:39:48Z |
| format | Article |
| id | doaj.art-df0c5e83089142c1a5682067d9b4b020 |
| institution | Directory Open Access Journal |
| issn | 1309-2251 |
| language | English |
| last_indexed | 2024-03-13T04:39:48Z |
| publishDate | 2022-01-01 |
| publisher | Kafkas University, Faculty of Veterinary Medicine |
| record_format | Article |
| series | Kafkas Universitesi Veteriner Fakültesi Dergisi |
| spelling | doaj.art-df0c5e83089142c1a5682067d9b4b0202023-06-19T06:28:21ZengKafkas University, Faculty of Veterinary MedicineKafkas Universitesi Veteriner Fakültesi Dergisi1309-22512022-01-0128218519110.9775/kvfd.2021.266542883Evaluation of the effects of new combined adsorbent on occurrence of pathological lesions in aflatoxin b1‐challenged broiler chickensBiljana DJURDJEVIĆ0Marko PAJIĆ1Slobodan KNEŽEVIĆ2Vladimir POLAČEK3Ksenija NEŠIĆ4Ivana VUČIĆEVIĆ5Dušica OSTOJIĆ ANDRIĆ6Scientific Veterinary Institute “Novi Sad”, Department for epizootiology, clinical diagnostic and DDD, 21000 Novi Sad, SERBIAScientific Veterinary Institute “Novi Sad”, Department for epizootiology, clinical diagnostic and DDD, 21000 Novi Sad, SERBIAScientific Veterinary Institute “Novi Sad”, Department for epizootiology, clinical diagnostic and DDD, 21000 Novi Sad, SERBIAScientific Veterinary Institute of Serbia, Department of food and feed quality and safety, 11070 Belgrade, SERBIAScientific Veterinary Institute of Serbia, Department of food and feed quality and safety, 11070 Belgrade, SERBIAUniversity of Belgrade, Faculty of Veterinary Medicine, Department of Pathology, 11000 Belgrade, SERBIAInstitute for Animal Husbandry, Department of Animal Breeding and Genetics, 11080 Zemun-Belgrade, SERBIAThis experiment was performed to investigate the protective eff ect of a new combined adsorbent (bentonite + yeast cell wall extract) previously tested in vitro, on the occurrence of pathological lesions in broilers fed a diet contaminated with afl atoxin B1 until 21 days of age. A total of 96 one-day old Ross 308 hybrid broiler chickens were divided into four groups: group I (control), group II (5 g/kg adsorbent), group III (5 g/kg adsorbent + 2 mg/kg afl atoxin B1), and group IV (2 mg/kg afl atoxin B1). Grossly, AFB1 and AFB1+adsorbent fed birds showed enlargement, friable texture of liver and enlargement and pallorness of kidneys. Spleen revealed size reduction. No gross-pathological changes were observed in control and group II. Histopathologically, lesions were observed in afl atoxicated groups. Liver revealed vacuolar cell degeneration, periportal and perivascular infiltration of mononuclear cells. Kidneys revealed mild to moderate degree of haemorrhages, tubular epithelial necrosis and infiltration of mononuclear cells along with heterophils. In group IV, catarrhal enteritis characterized by desquamation of epithelial cells were found in the duodenum. A milder form of gross and histopathological lesions was seen in group III. In conclusion, the present study revealed that supplementation of a new combined toxin binder product in the concentration of 5 g/kg could not completely ameliorate afl atoxicity in broilers, although it met the stringent European regulation requirements for the minimum of 90% afl atoxin binding efficiency in in vitro study.https://vetdergikafkas.org/pdf.php?id=2883adsorbentafl atoxin b1broilerspathological lesions |
| spellingShingle | Biljana DJURDJEVIĆ Marko PAJIĆ Slobodan KNEŽEVIĆ Vladimir POLAČEK Ksenija NEŠIĆ Ivana VUČIĆEVIĆ Dušica OSTOJIĆ ANDRIĆ Evaluation of the effects of new combined adsorbent on occurrence of pathological lesions in aflatoxin b1‐challenged broiler chickens Kafkas Universitesi Veteriner Fakültesi Dergisi adsorbent afl atoxin b1 broilers pathological lesions |
| title | Evaluation of the effects of new combined adsorbent on occurrence of pathological lesions in aflatoxin b1‐challenged broiler chickens |
| title_full | Evaluation of the effects of new combined adsorbent on occurrence of pathological lesions in aflatoxin b1‐challenged broiler chickens |
| title_fullStr | Evaluation of the effects of new combined adsorbent on occurrence of pathological lesions in aflatoxin b1‐challenged broiler chickens |
| title_full_unstemmed | Evaluation of the effects of new combined adsorbent on occurrence of pathological lesions in aflatoxin b1‐challenged broiler chickens |
| title_short | Evaluation of the effects of new combined adsorbent on occurrence of pathological lesions in aflatoxin b1‐challenged broiler chickens |
| title_sort | evaluation of the effects of new combined adsorbent on occurrence of pathological lesions in aflatoxin b1 challenged broiler chickens |
| topic | adsorbent afl atoxin b1 broilers pathological lesions |
| url | https://vetdergikafkas.org/pdf.php?id=2883 |
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