Novel Diphenylamine Analogs Induce Mesenchymal to Epithelial Transition in Triple Negative Breast Cancer

Novel Diphenylamine Analogs Induce Mesenchymal to Epithelial Transition in Triple Negative Breast Cancer

Epithelial to mesenchymal transition (EMT) is a cellular program that converts non-motile epithelial cells into invasive mesenchymal cells. EMT is implicated in cancer metastasis, chemo-resistance, cancer progression, and generation of cancer stem cells (CSCs). Inducing mesenchymal to epithelial tra...

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Bibliographic Details
Main Authors: Akshita B. Bhatt, Mohit Gupta, Van T. Hoang, Suravi Chakrabarty, Thomas D. Wright, Steven Elliot, Ishveen K. Chopra, Darlene Monlish, Katie Anna, Matthew E. Burow, Jane E. Cavanaugh, Patrick T. Flaherty
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Oncology
Subjects:
MET
EMT
phenotypic switch
mesenchymal
TNBC
MAPK
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00672/full

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