Novel Diphenylamine Analogs Induce Mesenchymal to Epithelial Transition in Triple Negative Breast Cancer

Novel Diphenylamine Analogs Induce Mesenchymal to Epithelial Transition in Triple Negative Breast Cancer

Epithelial to mesenchymal transition (EMT) is a cellular program that converts non-motile epithelial cells into invasive mesenchymal cells. EMT is implicated in cancer metastasis, chemo-resistance, cancer progression, and generation of cancer stem cells (CSCs). Inducing mesenchymal to epithelial tra...

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Podrobná bibliografie
Hlavní autoři: Akshita B. Bhatt, Mohit Gupta, Van T. Hoang, Suravi Chakrabarty, Thomas D. Wright, Steven Elliot, Ishveen K. Chopra, Darlene Monlish, Katie Anna, Matthew E. Burow, Jane E. Cavanaugh, Patrick T. Flaherty
Médium: Článek
Jazyk:English
Vydáno: Frontiers Media S.A. 2019-07-01
Edice:Frontiers in Oncology
Témata:
MET
EMT
phenotypic switch
mesenchymal
TNBC
MAPK
On-line přístup:https://www.frontiersin.org/article/10.3389/fonc.2019.00672/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2019.00672/full

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