Cytoreductive Surgery and Hyperthermic İntraperitoneal Chemoterapy for Advance Gastric Cancer Associated Peritoneal Carcinomatosis Single Centre Unit for 10 Consecutive Patients
Aim:Hyperthermic intraperitoneal chemotherapy with cytoreductive surgery has a positive effect on survival in advanced abdominal cancers. We aimed to present our experience with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in gastric cancer patients with peritoneal carcinomato...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Galenos Yayinevi
2019-09-01
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| Series: | Haseki Tıp Bülteni |
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http://www.hasekidergisi.com/archives/archive-detail/article-preview/cytoreductive-surgery-and-hyperthermic-intraperito/30304
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| _version_ | 1797906701861519360 |
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| author | Özgül Düzgün Sema Yüksekdağ Murat Kalın Şenol Çomoğlu Semra Yanık Ömer Faruk Özkan Neşet Köksal |
| author_facet | Özgül Düzgün Sema Yüksekdağ Murat Kalın Şenol Çomoğlu Semra Yanık Ömer Faruk Özkan Neşet Köksal |
| author_sort | Özgül Düzgün |
| collection | DOAJ |
| description | Aim:Hyperthermic intraperitoneal chemotherapy with cytoreductive surgery has a positive effect on survival in advanced abdominal cancers. We aimed to present our experience with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in gastric cancer patients with peritoneal carcinomatosis and a review of the literature.Methods:Ten patients (seven male, three female) who were diagnosed with gastric cancer between June 2017 and November 2018 were included in the study. Data on demographic characteristics, short-term follow-up results, surgical findings, peritoneal carcinomatosis index score, completeness of cytoreduction score, and morbidity and mortality rates were retrospectively analyzed.Results:The mean age of the patients was 60.3 years. The mean follow-up period was six months (1-15 months). One patient developed an anastomotic leak. In the other nine cases, there was no morbidity leading to mortality.Conclusion:While gastric cancer with peritoneal carcinomatos has a poor survival, less than six months with non-operative approach, treatment with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy offers better outcomes and overall survival. Our first results in our study with a limited number of patients are satisfactory and multicentric randomized studies are needed on this subject. |
| first_indexed | 2024-04-10T10:24:48Z |
| format | Article |
| id | doaj.art-df17ee32c0874e1eb0f472160f845d54 |
| institution | Directory Open Access Journal |
| issn | 1302-0072 2147-2688 |
| language | English |
| last_indexed | 2024-04-10T10:24:48Z |
| publishDate | 2019-09-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Haseki Tıp Bülteni |
| spelling | doaj.art-df17ee32c0874e1eb0f472160f845d542023-02-15T16:21:27ZengGalenos YayineviHaseki Tıp Bülteni1302-00722147-26882019-09-0157326727310.4274/haseki.galenos.2019.499713049054Cytoreductive Surgery and Hyperthermic İntraperitoneal Chemoterapy for Advance Gastric Cancer Associated Peritoneal Carcinomatosis Single Centre Unit for 10 Consecutive PatientsÖzgül Düzgün0Sema Yüksekdağ1Murat Kalın2Şenol Çomoğlu3Semra Yanık4Ömer Faruk Özkan5Neşet Köksal6 Sağlık Bilimleri Üniversitesi, Ümraniye Eğitim ve Araştırma Hastanesi, Genel Cerrahi Kliniği, İstanbul, Türkiye Sağlık Bilimleri Üniversitesi, Ümraniye Eğitim ve Araştırma Hastanesi, Genel Cerrahi Kliniği, İstanbul, Türkiye Sağlık Bilimleri Üniversitesi, Ümraniye Eğitim ve Araştırma Hastanesi, Genel Cerrahi Kliniği, İstanbul, Türkiye Sağlık Bilimleri Üniversitesi, Ümraniye Eğitim ve Araştırma Hastanesi, Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Kliniği, İstanbul, Türkiye Sağlık Bilimleri Üniversitesi, Ümraniye Eğitim ve Araştırma Hastanesi, Anestezi ve Reanimasyon Kliniği, İstanbul, Türkiye Sağlık Bilimleri Üniversitesi, Ümraniye Eğitim ve Araştırma Hastanesi, Genel Cerrahi Kliniği, İstanbul, Türkiye Yeditepe Üniversitesi Tıp Fakültesi Hastanesi, Genel Cerrahi Kliniği, İstanbul, Türkiye Aim:Hyperthermic intraperitoneal chemotherapy with cytoreductive surgery has a positive effect on survival in advanced abdominal cancers. We aimed to present our experience with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in gastric cancer patients with peritoneal carcinomatosis and a review of the literature.Methods:Ten patients (seven male, three female) who were diagnosed with gastric cancer between June 2017 and November 2018 were included in the study. Data on demographic characteristics, short-term follow-up results, surgical findings, peritoneal carcinomatosis index score, completeness of cytoreduction score, and morbidity and mortality rates were retrospectively analyzed.Results:The mean age of the patients was 60.3 years. The mean follow-up period was six months (1-15 months). One patient developed an anastomotic leak. In the other nine cases, there was no morbidity leading to mortality.Conclusion:While gastric cancer with peritoneal carcinomatos has a poor survival, less than six months with non-operative approach, treatment with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy offers better outcomes and overall survival. Our first results in our study with a limited number of patients are satisfactory and multicentric randomized studies are needed on this subject. http://www.hasekidergisi.com/archives/archive-detail/article-preview/cytoreductive-surgery-and-hyperthermic-intraperito/30304 Gastric cancerperitoneal carcinomatosiscytoreductive surgeryhyperthermic intraperitoneal chemotherapy |
| spellingShingle | Özgül Düzgün Sema Yüksekdağ Murat Kalın Şenol Çomoğlu Semra Yanık Ömer Faruk Özkan Neşet Köksal Cytoreductive Surgery and Hyperthermic İntraperitoneal Chemoterapy for Advance Gastric Cancer Associated Peritoneal Carcinomatosis Single Centre Unit for 10 Consecutive Patients Haseki Tıp Bülteni Gastric cancer peritoneal carcinomatosis cytoreductive surgery hyperthermic intraperitoneal chemotherapy |
| title | Cytoreductive Surgery and Hyperthermic İntraperitoneal Chemoterapy for Advance Gastric Cancer Associated Peritoneal Carcinomatosis Single Centre Unit for 10 Consecutive Patients |
| title_full | Cytoreductive Surgery and Hyperthermic İntraperitoneal Chemoterapy for Advance Gastric Cancer Associated Peritoneal Carcinomatosis Single Centre Unit for 10 Consecutive Patients |
| title_fullStr | Cytoreductive Surgery and Hyperthermic İntraperitoneal Chemoterapy for Advance Gastric Cancer Associated Peritoneal Carcinomatosis Single Centre Unit for 10 Consecutive Patients |
| title_full_unstemmed | Cytoreductive Surgery and Hyperthermic İntraperitoneal Chemoterapy for Advance Gastric Cancer Associated Peritoneal Carcinomatosis Single Centre Unit for 10 Consecutive Patients |
| title_short | Cytoreductive Surgery and Hyperthermic İntraperitoneal Chemoterapy for Advance Gastric Cancer Associated Peritoneal Carcinomatosis Single Centre Unit for 10 Consecutive Patients |
| title_sort | cytoreductive surgery and hyperthermic intraperitoneal chemoterapy for advance gastric cancer associated peritoneal carcinomatosis single centre unit for 10 consecutive patients |
| topic | Gastric cancer peritoneal carcinomatosis cytoreductive surgery hyperthermic intraperitoneal chemotherapy |
| url |
http://www.hasekidergisi.com/archives/archive-detail/article-preview/cytoreductive-surgery-and-hyperthermic-intraperito/30304
|
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