Combination of levofloxacin and cisplatin enhances anticancer efficacy via co-regulation of eight cancer-associated genes

Combination of levofloxacin and cisplatin enhances anticancer efficacy via co-regulation of eight cancer-associated genes

Abstract Chemosensitizer or combined chemotherapy can sensitize cancer cells to therapy and minimize drug resistance. We reveal that levofloxacin has broad-spectrum anticancer activity. Here we report that combination of levofloxacin and cisplatin further enhanced cytotoxicity in cancer cells by fur...

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Bibliographic Details
Main Authors: Xiaoqiong He, ·Qian Yao, Dan Fan, Yutong You, Wenjing Lian, Zhangping Zhou, Ling Duan
Format: Article
Language:English
Published: Springer 2022-08-01
Series:Discover Oncology
Subjects:
Levofloxacin
Cisplatin
Chemosensitizer
Combined chemotherapy
Drug repositioning
Online Access:https://doi.org/10.1007/s12672-022-00541-x

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