Metal-responsive promoter DNA compaction by the ferric uptake regulator
The Fur protein regulates transcription of bacterial genes in response to metal ions. Here, the authors show that the Fur protein from Helicobacter pylorirepresses transcription by iron-responsive oligomerization and DNA compaction, encasing the transcriptional start site in a macromolecular complex...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2016-08-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/ncomms12593 |
| _version_ | 1819129510521470976 |
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| author | Davide Roncarati Simone Pelliciari Nicola Doniselli Stefano Maggi Andrea Vannini Luca Valzania Luca Mazzei Barbara Zambelli Claudio Rivetti Alberto Danielli |
| author_facet | Davide Roncarati Simone Pelliciari Nicola Doniselli Stefano Maggi Andrea Vannini Luca Valzania Luca Mazzei Barbara Zambelli Claudio Rivetti Alberto Danielli |
| author_sort | Davide Roncarati |
| collection | DOAJ |
| description | The Fur protein regulates transcription of bacterial genes in response to metal ions. Here, the authors show that the Fur protein from Helicobacter pylorirepresses transcription by iron-responsive oligomerization and DNA compaction, encasing the transcriptional start site in a macromolecular complex. |
| first_indexed | 2024-12-22T08:44:52Z |
| format | Article |
| id | doaj.art-df1a4b051ef64998b7f2d859a4491d54 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-22T08:44:52Z |
| publishDate | 2016-08-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-df1a4b051ef64998b7f2d859a4491d542022-12-21T18:32:08ZengNature PortfolioNature Communications2041-17232016-08-017111310.1038/ncomms12593Metal-responsive promoter DNA compaction by the ferric uptake regulatorDavide Roncarati0Simone Pelliciari1Nicola Doniselli2Stefano Maggi3Andrea Vannini4Luca Valzania5Luca Mazzei6Barbara Zambelli7Claudio Rivetti8Alberto Danielli9Department of Pharmacy and Biotechnology (FaBiT), University of BolognaDepartment of Pharmacy and Biotechnology (FaBiT), University of BolognaDepartment of Life Sciences, University of ParmaDepartment of Life Sciences, University of ParmaDepartment of Pharmacy and Biotechnology (FaBiT), University of BolognaDepartment of Pharmacy and Biotechnology (FaBiT), University of BolognaDepartment of Pharmacy and Biotechnology (FaBiT), University of BolognaDepartment of Pharmacy and Biotechnology (FaBiT), University of BolognaDepartment of Life Sciences, University of ParmaDepartment of Pharmacy and Biotechnology (FaBiT), University of BolognaThe Fur protein regulates transcription of bacterial genes in response to metal ions. Here, the authors show that the Fur protein from Helicobacter pylorirepresses transcription by iron-responsive oligomerization and DNA compaction, encasing the transcriptional start site in a macromolecular complex.https://doi.org/10.1038/ncomms12593 |
| spellingShingle | Davide Roncarati Simone Pelliciari Nicola Doniselli Stefano Maggi Andrea Vannini Luca Valzania Luca Mazzei Barbara Zambelli Claudio Rivetti Alberto Danielli Metal-responsive promoter DNA compaction by the ferric uptake regulator Nature Communications |
| title | Metal-responsive promoter DNA compaction by the ferric uptake regulator |
| title_full | Metal-responsive promoter DNA compaction by the ferric uptake regulator |
| title_fullStr | Metal-responsive promoter DNA compaction by the ferric uptake regulator |
| title_full_unstemmed | Metal-responsive promoter DNA compaction by the ferric uptake regulator |
| title_short | Metal-responsive promoter DNA compaction by the ferric uptake regulator |
| title_sort | metal responsive promoter dna compaction by the ferric uptake regulator |
| url | https://doi.org/10.1038/ncomms12593 |
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