Extraction of glycyrrhizic acid by aqueous two-phase system formed by PEG and two environmentally friendly organic acid salts - sodium citrate and sodium tartrate
Two aqueous two-phase systems (ATPS’s) formed by using PEG and sodium citrate/sodium tartrate are applied and compared for extraction of glycyrrhizic acid (GA) from its stock solution. Their binodal curves and tie-lines are studied firstly. Influence of usage amount of the salt and the PEG on the pa...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
De Gruyter
2019-01-01
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| Series: | Green Processing and Synthesis |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/gps-2019-0024 |
| _version_ | 1818907740559376384 |
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| author | Zhang Zhi Feng Wang Rui Ye Fei Wang Haibin Zhao Wenxia |
| author_facet | Zhang Zhi Feng Wang Rui Ye Fei Wang Haibin Zhao Wenxia |
| author_sort | Zhang Zhi Feng |
| collection | DOAJ |
| description | Two aqueous two-phase systems (ATPS’s) formed by using PEG and sodium citrate/sodium tartrate are applied and compared for extraction of glycyrrhizic acid (GA) from its stock solution. Their binodal curves and tie-lines are studied firstly. Influence of usage amount of the salt and the PEG on the partition coefficient and extraction efficiency is investigated. The highest extraction efficiency and partition coefficient achieved is 73% and 6.5, when the sodium citrate and PEG concentration is 15% and 20% respectively. It is also found that the ATPS based on sodium citrate is better than sodium tartrate for GA extraction. The present study indicates that ATPS formed by biodegradable organic acid salts could be feasible and environment-friendly technique for GA and other bioactive compounds. |
| first_indexed | 2024-12-19T21:59:56Z |
| format | Article |
| id | doaj.art-df1f4e7e095f4e1a981134f1573c4f61 |
| institution | Directory Open Access Journal |
| issn | 2191-9550 |
| language | English |
| last_indexed | 2024-12-19T21:59:56Z |
| publishDate | 2019-01-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Green Processing and Synthesis |
| spelling | doaj.art-df1f4e7e095f4e1a981134f1573c4f612022-12-21T20:04:11ZengDe GruyterGreen Processing and Synthesis2191-95502019-01-018155155610.1515/gps-2019-0024gps-2019-0024Extraction of glycyrrhizic acid by aqueous two-phase system formed by PEG and two environmentally friendly organic acid salts - sodium citrate and sodium tartrateZhang Zhi Feng0Wang Rui1Ye Fei2Wang Haibin3Zhao Wenxia4College of Chemistry and Chemical Engineering, Ningxia Normal University, Guyuan, Ningxia, China, 756000College of Chemistry and Chemical Engineering, Ningxia Normal University, Guyuan, Ningxia, China, 756000College of Chemistry and Chemical Engineering, Ningxia Normal University, Guyuan, Ningxia, China, 756000College of Chemistry and Chemical Engineering, Ningxia Normal University, Guyuan, Ningxia, China, 756000College of Chemistry and Chemical Engineering, Ningxia Normal University, Guyuan, Ningxia, China, 756000Two aqueous two-phase systems (ATPS’s) formed by using PEG and sodium citrate/sodium tartrate are applied and compared for extraction of glycyrrhizic acid (GA) from its stock solution. Their binodal curves and tie-lines are studied firstly. Influence of usage amount of the salt and the PEG on the partition coefficient and extraction efficiency is investigated. The highest extraction efficiency and partition coefficient achieved is 73% and 6.5, when the sodium citrate and PEG concentration is 15% and 20% respectively. It is also found that the ATPS based on sodium citrate is better than sodium tartrate for GA extraction. The present study indicates that ATPS formed by biodegradable organic acid salts could be feasible and environment-friendly technique for GA and other bioactive compounds.https://doi.org/10.1515/gps-2019-0024glycyrrhizic acidlicoriceaqueous two-phase systemextraction |
| spellingShingle | Zhang Zhi Feng Wang Rui Ye Fei Wang Haibin Zhao Wenxia Extraction of glycyrrhizic acid by aqueous two-phase system formed by PEG and two environmentally friendly organic acid salts - sodium citrate and sodium tartrate Green Processing and Synthesis glycyrrhizic acid licorice aqueous two-phase system extraction |
| title | Extraction of glycyrrhizic acid by aqueous two-phase system formed by PEG and two environmentally friendly organic acid salts - sodium citrate and sodium tartrate |
| title_full | Extraction of glycyrrhizic acid by aqueous two-phase system formed by PEG and two environmentally friendly organic acid salts - sodium citrate and sodium tartrate |
| title_fullStr | Extraction of glycyrrhizic acid by aqueous two-phase system formed by PEG and two environmentally friendly organic acid salts - sodium citrate and sodium tartrate |
| title_full_unstemmed | Extraction of glycyrrhizic acid by aqueous two-phase system formed by PEG and two environmentally friendly organic acid salts - sodium citrate and sodium tartrate |
| title_short | Extraction of glycyrrhizic acid by aqueous two-phase system formed by PEG and two environmentally friendly organic acid salts - sodium citrate and sodium tartrate |
| title_sort | extraction of glycyrrhizic acid by aqueous two phase system formed by peg and two environmentally friendly organic acid salts sodium citrate and sodium tartrate |
| topic | glycyrrhizic acid licorice aqueous two-phase system extraction |
| url | https://doi.org/10.1515/gps-2019-0024 |
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