Recent Advances in Translational Pharmacokinetics and Pharmacodynamics Prediction of Therapeutic Antibodies Using Modeling and Simulation

Recent Advances in Translational Pharmacokinetics and Pharmacodynamics Prediction of Therapeutic Antibodies Using Modeling and Simulation

Therapeutic monoclonal antibodies (mAbs) have been a promising therapeutic approach for several diseases and a wide variety of mAbs are being evaluated in clinical trials. To accelerate clinical development and improve the probability of success, pharmacokinetics and pharmacodynamics (PKPD) in human...

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Bibliographic Details
Main Authors:	Kenta Haraya, Haruka Tsutsui, Yasunori Komori, Tatsuhiko Tachibana
Format:	Article
Language:	English
Published:	MDPI AG 2022-04-01
Series:	Pharmaceuticals
Subjects:	therapeutic monoclonal antibodies pharmacokinetics pharmacodynamics modeling and simulation human prediction TMDD
Online Access:	https://www.mdpi.com/1424-8247/15/5/508

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