Functional characterization of MEKK3 in the intestinal immune response to bacterial challenges in grass carp (Ctenopharyngodon idella)

Functional characterization of MEKK3 in the intestinal immune response to bacterial challenges in grass carp (Ctenopharyngodon idella)

Mitogen-activated protein kinase kinase kinase 3 (MEKK3) is an evolutionarily conserved Ser/Thr protein kinase of the MEKK family that is essential for the host immune response to pathogen challenges in mammals. However, the immune function of MEKK3s in lower vertebrate species, especially in bony f...

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Bibliographic Details
Main Authors: Fufa Qu, Xuan Zeng, Zhenzhen Liu, Meixing Guo, Xia Zhang, Shenping Cao, Yonghua Zhou, Zhimin He, Jianzhou Tang, Zhuangwen Mao, Yalin Yang, Zhigang Zhou, Zhen Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Immunology
Subjects:
grass carp
MEKK3
molecular characterization
bacterial challenge
intestinal immunity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.981995/full

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