Expanding role of self expanding esophageal stents

Esophageal cancer is often diagnosed at a late stage and hence carries a poor prognosis with an overall 5-year survival rate of 10% to 15%. Therefore, palliative treatment primarily aimed at the relieving dysphagia is the only available option. Endoscopic placement of self expanding metal stents (SE...

Full description

Bibliographic Details
Main Author: Kulwinder S Dua
Format: Article
Language:English
Published: Thieme Medical and Scientific Publishers Pvt. Ltd. 2011-01-01
Series:Journal of Digestive Endoscopy
Subjects:
Online Access:http://www.jdeonline.in/article.asp?issn=0976-5042;year=2011;volume=2;issue=1;spage=9;epage=14;aulast=Dua
_version_ 1819264330694131712
author Kulwinder S Dua
author_facet Kulwinder S Dua
author_sort Kulwinder S Dua
collection DOAJ
description Esophageal cancer is often diagnosed at a late stage and hence carries a poor prognosis with an overall 5-year survival rate of 10% to 15%. Therefore, palliative treatment primarily aimed at the relieving dysphagia is the only available option. Endoscopic placement of self expanding metal stents (SEMS) has become a widely used method for palliation offering prompt relief of dysphagia and numerous reports have shown it to be safe and effective. Secondary to tissue in-growth into the uncovered segments of the stent, SEMS cannot be removed and hence are not approved for benign indications. With the advent of the removable self expanding plastic stents, the indications for esophageal stent insertion have expanded to as bridge to surgery for patients undergoing neoadjuvant chemotherapy, for refractory benign esophageal strictures, for non-malignant esophageal perforations, leaks and fistulae, and even for variceal hemorrhage. Newer fully covered SEMS that are potentially removable are also being tried for benign indications but await FDA clearance. Similarly biodegradeable stents for benign disorders and radioactive or drug-eluding stents for malignant disease are hoped to improve the management of esophageal diseases. The purpose of this article is to review the expanding role of self expanding stents in the management of esophageal disorders other than palliating malignant dysphagia and fistulae.
first_indexed 2024-12-23T20:27:46Z
format Article
id doaj.art-df22bc05545d45508b4ab350316f9f30
institution Directory Open Access Journal
issn 0976-5042
0976-5050
language English
last_indexed 2024-12-23T20:27:46Z
publishDate 2011-01-01
publisher Thieme Medical and Scientific Publishers Pvt. Ltd.
record_format Article
series Journal of Digestive Endoscopy
spelling doaj.art-df22bc05545d45508b4ab350316f9f302022-12-21T17:32:20ZengThieme Medical and Scientific Publishers Pvt. Ltd.Journal of Digestive Endoscopy0976-50420976-50502011-01-0121914Expanding role of self expanding esophageal stentsKulwinder S DuaEsophageal cancer is often diagnosed at a late stage and hence carries a poor prognosis with an overall 5-year survival rate of 10% to 15%. Therefore, palliative treatment primarily aimed at the relieving dysphagia is the only available option. Endoscopic placement of self expanding metal stents (SEMS) has become a widely used method for palliation offering prompt relief of dysphagia and numerous reports have shown it to be safe and effective. Secondary to tissue in-growth into the uncovered segments of the stent, SEMS cannot be removed and hence are not approved for benign indications. With the advent of the removable self expanding plastic stents, the indications for esophageal stent insertion have expanded to as bridge to surgery for patients undergoing neoadjuvant chemotherapy, for refractory benign esophageal strictures, for non-malignant esophageal perforations, leaks and fistulae, and even for variceal hemorrhage. Newer fully covered SEMS that are potentially removable are also being tried for benign indications but await FDA clearance. Similarly biodegradeable stents for benign disorders and radioactive or drug-eluding stents for malignant disease are hoped to improve the management of esophageal diseases. The purpose of this article is to review the expanding role of self expanding stents in the management of esophageal disorders other than palliating malignant dysphagia and fistulae.http://www.jdeonline.in/article.asp?issn=0976-5042;year=2011;volume=2;issue=1;spage=9;epage=14;aulast=DuaEsophageal cancer -Malignant dysphagia -Refractory benign esophageal stricture -Esophageal perforation leaks -Fistulae -Self expanding metalstent -Self expanding polyflexstent -Biodegradeable esophageal stent
spellingShingle Kulwinder S Dua
Expanding role of self expanding esophageal stents
Journal of Digestive Endoscopy
Esophageal cancer -Malignant dysphagia -Refractory benign esophageal stricture -Esophageal perforation leaks -Fistulae -Self expanding metalstent -Self expanding polyflexstent -Biodegradeable esophageal stent
title Expanding role of self expanding esophageal stents
title_full Expanding role of self expanding esophageal stents
title_fullStr Expanding role of self expanding esophageal stents
title_full_unstemmed Expanding role of self expanding esophageal stents
title_short Expanding role of self expanding esophageal stents
title_sort expanding role of self expanding esophageal stents
topic Esophageal cancer -Malignant dysphagia -Refractory benign esophageal stricture -Esophageal perforation leaks -Fistulae -Self expanding metalstent -Self expanding polyflexstent -Biodegradeable esophageal stent
url http://www.jdeonline.in/article.asp?issn=0976-5042;year=2011;volume=2;issue=1;spage=9;epage=14;aulast=Dua
work_keys_str_mv AT kulwindersdua expandingroleofselfexpandingesophagealstents