Risk Factors Associated with Linkage to Care among Suburban Hepatitis C-Positive Baby Boomers and Injection Drug Users
Abstract Introduction Suffolk County, located in Eastern Long Island, has been an epicenter for the opioid epidemic in New York State, yet no studies have examined hepatitis C virus (HCV) prevalence in this population. Additionally, few studies have assessed barriers for linkage to care (LTC) to HCV...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Adis, Springer Healthcare
2019-05-01
|
| Series: | Infectious Diseases and Therapy |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1007/s40121-019-0249-y |
| _version_ | 1818881361164894208 |
|---|---|
| author | Audun J. Lier Kalie Smith Kerim Odekon Silvia Bronson Erin Taub Mathew Tharakan Gerald J. Kelly Pruthvi Patel Luis A. Marcos |
| author_facet | Audun J. Lier Kalie Smith Kerim Odekon Silvia Bronson Erin Taub Mathew Tharakan Gerald J. Kelly Pruthvi Patel Luis A. Marcos |
| author_sort | Audun J. Lier |
| collection | DOAJ |
| description | Abstract Introduction Suffolk County, located in Eastern Long Island, has been an epicenter for the opioid epidemic in New York State, yet no studies have examined hepatitis C virus (HCV) prevalence in this population. Additionally, few studies have assessed barriers for linkage to care (LTC) to HCV treatment in people who inject drugs (PWID), a high-risk HCV cohort. We aimed to determine prevalence of HCV infection in a suburban medical center and to assess risk factors associated with LTC in HCV-positive baby boomers and young PWID. Methods A retrospective chart review was carried out on adult patients with ICD-9/10 diagnostic codes for HCV from January 2016 to December 2018 at Stony Brook Medicine. Data collected included sociodemographics, RNA serostatus, LTC, health insurance, employment, past medical or psychiatric history, and substance or injection drug use. Results Overall, 27,049 individuals were screened for HCV and 1017 were HCV seropositive (3.8%), 437 (42.9%) were HCV RNA-positive and 153 (40.6%) achieved LTC. In multivariate analysis, living with cirrhosis was associated with a positive LTC. Medicaid or Medicare insurance was associated with a negative LTC. Intravenous drug users were more likely to be young and have concomitant polysubstance use and psychiatric disease. A bimodal distribution of HCV-positives is present in our population. Conclusion Those with liver cirrhosis are more likely to achieve LTC, as are those with private insurance. Public health efforts to promote awareness of HCV and to facilitate access to treatment among PWID are needed. |
| first_indexed | 2024-12-19T15:00:38Z |
| format | Article |
| id | doaj.art-df2336acfe4b4d2e8ad7867f39c47d48 |
| institution | Directory Open Access Journal |
| issn | 2193-8229 2193-6382 |
| language | English |
| last_indexed | 2024-12-19T15:00:38Z |
| publishDate | 2019-05-01 |
| publisher | Adis, Springer Healthcare |
| record_format | Article |
| series | Infectious Diseases and Therapy |
| spelling | doaj.art-df2336acfe4b4d2e8ad7867f39c47d482022-12-21T20:16:35ZengAdis, Springer HealthcareInfectious Diseases and Therapy2193-82292193-63822019-05-018341742810.1007/s40121-019-0249-yRisk Factors Associated with Linkage to Care among Suburban Hepatitis C-Positive Baby Boomers and Injection Drug UsersAudun J. Lier0Kalie Smith1Kerim Odekon2Silvia Bronson3Erin Taub4Mathew Tharakan5Gerald J. Kelly6Pruthvi Patel7Luis A. Marcos8Department of Internal Medicine, Stony Brook University HospitalDivision of Infectious Diseases, Department of Internal Medicine, Stony Brook University HospitalDepartment of Internal Medicine, Stony Brook University HospitalDivision of Infectious Diseases, Department of Internal Medicine, Stony Brook University HospitalDepartment of Internal Medicine, Stony Brook University HospitalDepartment of Internal Medicine, Stony Brook University HospitalDivision of Family and Community Medicine, Department of Family, Population and Preventive Medicine, Stony Brook University HospitalDivision of Gastroenterology, Department of Internal Medicine, Stony Brook University HospitalDivision of Infectious Diseases, Department of Internal Medicine, Stony Brook University HospitalAbstract Introduction Suffolk County, located in Eastern Long Island, has been an epicenter for the opioid epidemic in New York State, yet no studies have examined hepatitis C virus (HCV) prevalence in this population. Additionally, few studies have assessed barriers for linkage to care (LTC) to HCV treatment in people who inject drugs (PWID), a high-risk HCV cohort. We aimed to determine prevalence of HCV infection in a suburban medical center and to assess risk factors associated with LTC in HCV-positive baby boomers and young PWID. Methods A retrospective chart review was carried out on adult patients with ICD-9/10 diagnostic codes for HCV from January 2016 to December 2018 at Stony Brook Medicine. Data collected included sociodemographics, RNA serostatus, LTC, health insurance, employment, past medical or psychiatric history, and substance or injection drug use. Results Overall, 27,049 individuals were screened for HCV and 1017 were HCV seropositive (3.8%), 437 (42.9%) were HCV RNA-positive and 153 (40.6%) achieved LTC. In multivariate analysis, living with cirrhosis was associated with a positive LTC. Medicaid or Medicare insurance was associated with a negative LTC. Intravenous drug users were more likely to be young and have concomitant polysubstance use and psychiatric disease. A bimodal distribution of HCV-positives is present in our population. Conclusion Those with liver cirrhosis are more likely to achieve LTC, as are those with private insurance. Public health efforts to promote awareness of HCV and to facilitate access to treatment among PWID are needed.http://link.springer.com/article/10.1007/s40121-019-0249-yHepatitis C virusIntravenous drug abuseLinkage to careRisk factors |
| spellingShingle | Audun J. Lier Kalie Smith Kerim Odekon Silvia Bronson Erin Taub Mathew Tharakan Gerald J. Kelly Pruthvi Patel Luis A. Marcos Risk Factors Associated with Linkage to Care among Suburban Hepatitis C-Positive Baby Boomers and Injection Drug Users Infectious Diseases and Therapy Hepatitis C virus Intravenous drug abuse Linkage to care Risk factors |
| title | Risk Factors Associated with Linkage to Care among Suburban Hepatitis C-Positive Baby Boomers and Injection Drug Users |
| title_full | Risk Factors Associated with Linkage to Care among Suburban Hepatitis C-Positive Baby Boomers and Injection Drug Users |
| title_fullStr | Risk Factors Associated with Linkage to Care among Suburban Hepatitis C-Positive Baby Boomers and Injection Drug Users |
| title_full_unstemmed | Risk Factors Associated with Linkage to Care among Suburban Hepatitis C-Positive Baby Boomers and Injection Drug Users |
| title_short | Risk Factors Associated with Linkage to Care among Suburban Hepatitis C-Positive Baby Boomers and Injection Drug Users |
| title_sort | risk factors associated with linkage to care among suburban hepatitis c positive baby boomers and injection drug users |
| topic | Hepatitis C virus Intravenous drug abuse Linkage to care Risk factors |
| url | http://link.springer.com/article/10.1007/s40121-019-0249-y |
| work_keys_str_mv | AT audunjlier riskfactorsassociatedwithlinkagetocareamongsuburbanhepatitiscpositivebabyboomersandinjectiondrugusers AT kaliesmith riskfactorsassociatedwithlinkagetocareamongsuburbanhepatitiscpositivebabyboomersandinjectiondrugusers AT kerimodekon riskfactorsassociatedwithlinkagetocareamongsuburbanhepatitiscpositivebabyboomersandinjectiondrugusers AT silviabronson riskfactorsassociatedwithlinkagetocareamongsuburbanhepatitiscpositivebabyboomersandinjectiondrugusers AT erintaub riskfactorsassociatedwithlinkagetocareamongsuburbanhepatitiscpositivebabyboomersandinjectiondrugusers AT mathewtharakan riskfactorsassociatedwithlinkagetocareamongsuburbanhepatitiscpositivebabyboomersandinjectiondrugusers AT geraldjkelly riskfactorsassociatedwithlinkagetocareamongsuburbanhepatitiscpositivebabyboomersandinjectiondrugusers AT pruthvipatel riskfactorsassociatedwithlinkagetocareamongsuburbanhepatitiscpositivebabyboomersandinjectiondrugusers AT luisamarcos riskfactorsassociatedwithlinkagetocareamongsuburbanhepatitiscpositivebabyboomersandinjectiondrugusers |