Renal transplant immunosuppression impairs natural killer cell function in vitro and in vivo.

Renal transplant immunosuppression impairs natural killer cell function in vitro and in vivo.

Despite an increasing awareness of the importance of innate immunity, the roles of natural killer (NK) cells in transplant rejection and antiviral and cancer immunity during immunosuppression have not been clearly defined.To address this issue we have developed a quantitative assay of NK cell functi...

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Bibliographic Details
Main Authors: Olivier Morteau, Samkeliso Blundell, Aron Chakera, Sophia Bennett, Charita M Christou, Philip D Mason, Richard J Cornall, Christopher A O'Callaghan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2953494?pdf=render

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