Language lateralization in a patient with temporal lobe epilepsy and callosal agenesis
The corpus callosum has been proposed as a mechanism of interhemispheric inhibition that allows language dominance to develop [1]. Callosal agenesis or dysgenesis provides a test of this hypothesis, as patients lacking a normal corpus callosum should also lack normal language lateralization [2]. We...
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Format: | Article |
Language: | English |
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Elsevier
2015-01-01
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Series: | Epilepsy and Behavior Case Reports |
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Online Access: | http://www.sciencedirect.com/science/article/pii/S2213323214000346 |
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author | Taoufik Alsaadi Tarek M. Shahrour |
author_facet | Taoufik Alsaadi Tarek M. Shahrour |
author_sort | Taoufik Alsaadi |
collection | DOAJ |
description | The corpus callosum has been proposed as a mechanism of interhemispheric inhibition that allows language dominance to develop [1]. Callosal agenesis or dysgenesis provides a test of this hypothesis, as patients lacking a normal corpus callosum should also lack normal language lateralization [2]. We report pre- and postoperative functional magnetic resonance imaging (fMRI) and neuropsychological testing in a patient with partial callosal agenesis who underwent a right temporal lobectomy for medically refractory seizures. |
first_indexed | 2024-12-11T11:24:41Z |
format | Article |
id | doaj.art-df254817f1084176b52651fac862f11d |
institution | Directory Open Access Journal |
issn | 2213-3232 |
language | English |
last_indexed | 2024-12-11T11:24:41Z |
publishDate | 2015-01-01 |
publisher | Elsevier |
record_format | Article |
series | Epilepsy and Behavior Case Reports |
spelling | doaj.art-df254817f1084176b52651fac862f11d2022-12-22T01:09:02ZengElsevierEpilepsy and Behavior Case Reports2213-32322015-01-013C1310.1016/j.ebcr.2014.07.003Language lateralization in a patient with temporal lobe epilepsy and callosal agenesisTaoufik Alsaadi0Tarek M. Shahrour1Department of Neurology, SKMC, United Arab EmiratesDepartment of Psychiatry, SKMC, United Arab EmiratesThe corpus callosum has been proposed as a mechanism of interhemispheric inhibition that allows language dominance to develop [1]. Callosal agenesis or dysgenesis provides a test of this hypothesis, as patients lacking a normal corpus callosum should also lack normal language lateralization [2]. We report pre- and postoperative functional magnetic resonance imaging (fMRI) and neuropsychological testing in a patient with partial callosal agenesis who underwent a right temporal lobectomy for medically refractory seizures.http://www.sciencedirect.com/science/article/pii/S2213323214000346Callosal agenesisLanguage lateralizationfMRIEpilepsy |
spellingShingle | Taoufik Alsaadi Tarek M. Shahrour Language lateralization in a patient with temporal lobe epilepsy and callosal agenesis Epilepsy and Behavior Case Reports Callosal agenesis Language lateralization fMRI Epilepsy |
title | Language lateralization in a patient with temporal lobe epilepsy and callosal agenesis |
title_full | Language lateralization in a patient with temporal lobe epilepsy and callosal agenesis |
title_fullStr | Language lateralization in a patient with temporal lobe epilepsy and callosal agenesis |
title_full_unstemmed | Language lateralization in a patient with temporal lobe epilepsy and callosal agenesis |
title_short | Language lateralization in a patient with temporal lobe epilepsy and callosal agenesis |
title_sort | language lateralization in a patient with temporal lobe epilepsy and callosal agenesis |
topic | Callosal agenesis Language lateralization fMRI Epilepsy |
url | http://www.sciencedirect.com/science/article/pii/S2213323214000346 |
work_keys_str_mv | AT taoufikalsaadi languagelateralizationinapatientwithtemporallobeepilepsyandcallosalagenesis AT tarekmshahrour languagelateralizationinapatientwithtemporallobeepilepsyandcallosalagenesis |