Language lateralization in a patient with temporal lobe epilepsy and callosal agenesis

The corpus callosum has been proposed as a mechanism of interhemispheric inhibition that allows language dominance to develop [1]. Callosal agenesis or dysgenesis provides a test of this hypothesis, as patients lacking a normal corpus callosum should also lack normal language lateralization [2]. We...

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Main Authors: Taoufik Alsaadi, Tarek M. Shahrour
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:Epilepsy and Behavior Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213323214000346
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author Taoufik Alsaadi
Tarek M. Shahrour
author_facet Taoufik Alsaadi
Tarek M. Shahrour
author_sort Taoufik Alsaadi
collection DOAJ
description The corpus callosum has been proposed as a mechanism of interhemispheric inhibition that allows language dominance to develop [1]. Callosal agenesis or dysgenesis provides a test of this hypothesis, as patients lacking a normal corpus callosum should also lack normal language lateralization [2]. We report pre- and postoperative functional magnetic resonance imaging (fMRI) and neuropsychological testing in a patient with partial callosal agenesis who underwent a right temporal lobectomy for medically refractory seizures.
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spelling doaj.art-df254817f1084176b52651fac862f11d2022-12-22T01:09:02ZengElsevierEpilepsy and Behavior Case Reports2213-32322015-01-013C1310.1016/j.ebcr.2014.07.003Language lateralization in a patient with temporal lobe epilepsy and callosal agenesisTaoufik Alsaadi0Tarek M. Shahrour1Department of Neurology, SKMC, United Arab EmiratesDepartment of Psychiatry, SKMC, United Arab EmiratesThe corpus callosum has been proposed as a mechanism of interhemispheric inhibition that allows language dominance to develop [1]. Callosal agenesis or dysgenesis provides a test of this hypothesis, as patients lacking a normal corpus callosum should also lack normal language lateralization [2]. We report pre- and postoperative functional magnetic resonance imaging (fMRI) and neuropsychological testing in a patient with partial callosal agenesis who underwent a right temporal lobectomy for medically refractory seizures.http://www.sciencedirect.com/science/article/pii/S2213323214000346Callosal agenesisLanguage lateralizationfMRIEpilepsy
spellingShingle Taoufik Alsaadi
Tarek M. Shahrour
Language lateralization in a patient with temporal lobe epilepsy and callosal agenesis
Epilepsy and Behavior Case Reports
Callosal agenesis
Language lateralization
fMRI
Epilepsy
title Language lateralization in a patient with temporal lobe epilepsy and callosal agenesis
title_full Language lateralization in a patient with temporal lobe epilepsy and callosal agenesis
title_fullStr Language lateralization in a patient with temporal lobe epilepsy and callosal agenesis
title_full_unstemmed Language lateralization in a patient with temporal lobe epilepsy and callosal agenesis
title_short Language lateralization in a patient with temporal lobe epilepsy and callosal agenesis
title_sort language lateralization in a patient with temporal lobe epilepsy and callosal agenesis
topic Callosal agenesis
Language lateralization
fMRI
Epilepsy
url http://www.sciencedirect.com/science/article/pii/S2213323214000346
work_keys_str_mv AT taoufikalsaadi languagelateralizationinapatientwithtemporallobeepilepsyandcallosalagenesis
AT tarekmshahrour languagelateralizationinapatientwithtemporallobeepilepsyandcallosalagenesis