Ubiquitin-specific protease 1 acts as an oncogene and promotes lenvatinib efficacy in hepatocellular carcinoma by stabilizing c-kit

Ubiquitin-specific protease 1 acts as an oncogene and promotes lenvatinib efficacy in hepatocellular carcinoma by stabilizing c-kit

Introduction and Objectives: Ubiquitin-specific proteases (USPs) act as proto-oncogenes or tumor suppressors in a wide variety of cancers. In this study, we intended to explore the role of USP1 in hepatocellular carcinoma (HCC). Materials and Methods: The clinical significance of USP1 in HCC was ana...

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Bibliographic Details
Main Authors: Zhangbin Chen, Yifei Ma, Zhitang Guo, Dingyuan Song, Zili Chen, Min Sun
Format: Article
Language:English
Published: Elsevier 2022-03-01
Series:Annals of Hepatology
Subjects:
USP1
HCC
Lenvatinib
c-kit
Online Access:http://www.sciencedirect.com/science/article/pii/S1665268122000114

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