Blue rubber bleb nevus syndrome associated with adult-onset cutaneous lesions and spontaneous intracranial hemorrhage: A case report and literature review
Blue rubber bleb nevus syndrome (BRBNS) is a rare disorder. Since 1860, only 200 case reports of BRBNS have been reported. BRBNS is characterized by numerous malformations of the vascular system that significantly involve the skin, gastrointestinal tract, and other internal organs. We describe a 72-...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2018-09-01
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| Series: | Dermatologica Sinica |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S102781171730143X |
| _version_ | 1818109038360002560 |
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| author | Chia-Hua Lin Bai-Yao Wu Chih-Tsung Hung Hong-Wei Gao |
| author_facet | Chia-Hua Lin Bai-Yao Wu Chih-Tsung Hung Hong-Wei Gao |
| author_sort | Chia-Hua Lin |
| collection | DOAJ |
| description | Blue rubber bleb nevus syndrome (BRBNS) is a rare disorder. Since 1860, only 200 case reports of BRBNS have been reported. BRBNS is characterized by numerous malformations of the vascular system that significantly involve the skin, gastrointestinal tract, and other internal organs. We describe a 72-year-old Taiwanese man with BRBNS. Besides typical adult-onset cutaneous lesions, he had venous malformation in the central nervous system, which caused massive intracerebral hemorrhage. He has been in a stupor ever since. Physicians should recognize cutaneous BRBNS lesions early and be aware of the possible complications that arise from internal organs involved. Keywords: Bleeding, Central nervous system, Venous malformation, Blue rubber bleb syndrome, BRBNS |
| first_indexed | 2024-12-11T02:24:54Z |
| format | Article |
| id | doaj.art-df2d96e737ec45c59897db62833f4386 |
| institution | Directory Open Access Journal |
| issn | 1027-8117 |
| language | English |
| last_indexed | 2024-12-11T02:24:54Z |
| publishDate | 2018-09-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Dermatologica Sinica |
| spelling | doaj.art-df2d96e737ec45c59897db62833f43862022-12-22T01:23:58ZengWolters Kluwer Medknow PublicationsDermatologica Sinica1027-81172018-09-01363153156Blue rubber bleb nevus syndrome associated with adult-onset cutaneous lesions and spontaneous intracranial hemorrhage: A case report and literature reviewChia-Hua Lin0Bai-Yao Wu1Chih-Tsung Hung2Hong-Wei Gao3Department of Dermatology, Tri-Service General Hospital, National Defense Medical Center, Taipei, TaiwanDepartment of Dermatology, Tri-Service General Hospital, National Defense Medical Center, Taipei, TaiwanDepartment of Dermatology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan; Corresponding author. Department of Dermatology, Tri-Service General Hospital, 325, Cheng-Kung Road, Sec. 2, Taipei, 114, Taiwan. Fax: +886 2 8792 7181.Department of Pathology, Tri-Service General Hospital, National Defense Medical Center, Taipei, TaiwanBlue rubber bleb nevus syndrome (BRBNS) is a rare disorder. Since 1860, only 200 case reports of BRBNS have been reported. BRBNS is characterized by numerous malformations of the vascular system that significantly involve the skin, gastrointestinal tract, and other internal organs. We describe a 72-year-old Taiwanese man with BRBNS. Besides typical adult-onset cutaneous lesions, he had venous malformation in the central nervous system, which caused massive intracerebral hemorrhage. He has been in a stupor ever since. Physicians should recognize cutaneous BRBNS lesions early and be aware of the possible complications that arise from internal organs involved. Keywords: Bleeding, Central nervous system, Venous malformation, Blue rubber bleb syndrome, BRBNShttp://www.sciencedirect.com/science/article/pii/S102781171730143X |
| spellingShingle | Chia-Hua Lin Bai-Yao Wu Chih-Tsung Hung Hong-Wei Gao Blue rubber bleb nevus syndrome associated with adult-onset cutaneous lesions and spontaneous intracranial hemorrhage: A case report and literature review Dermatologica Sinica |
| title | Blue rubber bleb nevus syndrome associated with adult-onset cutaneous lesions and spontaneous intracranial hemorrhage: A case report and literature review |
| title_full | Blue rubber bleb nevus syndrome associated with adult-onset cutaneous lesions and spontaneous intracranial hemorrhage: A case report and literature review |
| title_fullStr | Blue rubber bleb nevus syndrome associated with adult-onset cutaneous lesions and spontaneous intracranial hemorrhage: A case report and literature review |
| title_full_unstemmed | Blue rubber bleb nevus syndrome associated with adult-onset cutaneous lesions and spontaneous intracranial hemorrhage: A case report and literature review |
| title_short | Blue rubber bleb nevus syndrome associated with adult-onset cutaneous lesions and spontaneous intracranial hemorrhage: A case report and literature review |
| title_sort | blue rubber bleb nevus syndrome associated with adult onset cutaneous lesions and spontaneous intracranial hemorrhage a case report and literature review |
| url | http://www.sciencedirect.com/science/article/pii/S102781171730143X |
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