Friction Determination by Atomic Force Microscopy in Field of Biochemical Science
Atomic force microscopy (AFM) is an analytical nanotechnology in friction determination between microscale and nanoscale surfaces. AFM has advantages in mechanical measurement, including high sensitivity, resolution, accuracy, and simplicity of operation. This paper will introduce the principles of...
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Format: | Article |
Language: | English |
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MDPI AG
2018-06-01
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Series: | Micromachines |
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Online Access: | http://www.mdpi.com/2072-666X/9/7/313 |
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author | Yan Wang Jianhua Wang |
author_facet | Yan Wang Jianhua Wang |
author_sort | Yan Wang |
collection | DOAJ |
description | Atomic force microscopy (AFM) is an analytical nanotechnology in friction determination between microscale and nanoscale surfaces. AFM has advantages in mechanical measurement, including high sensitivity, resolution, accuracy, and simplicity of operation. This paper will introduce the principles of mechanical measurement by using AFM and reviewing the progress of AFM methods in determining frictions in the field of biochemical science over the past decade. While three friction measurement assays—friction morphology, friction curve and friction process in experimental cases—are mainly introduced, important advances of technology, facilitating future development of AFM are also discussed. In addition to the principles and advances, the authors also give an overview of the shortcomings and restrictions of current AFM methods, and propose potential directions of AFM techniques by combining it with other well-established characterization techniques. AFM methods are expected to see an increase in development and attract wide attention in scientific research. |
first_indexed | 2024-12-21T17:51:25Z |
format | Article |
id | doaj.art-df2fc046714544b48ba2f0a3abc9ba59 |
institution | Directory Open Access Journal |
issn | 2072-666X |
language | English |
last_indexed | 2024-12-21T17:51:25Z |
publishDate | 2018-06-01 |
publisher | MDPI AG |
record_format | Article |
series | Micromachines |
spelling | doaj.art-df2fc046714544b48ba2f0a3abc9ba592022-12-21T18:55:21ZengMDPI AGMicromachines2072-666X2018-06-019731310.3390/mi9070313mi9070313Friction Determination by Atomic Force Microscopy in Field of Biochemical ScienceYan Wang0Jianhua Wang1College of Bioengineering, Chongqing University, Chongqing 400044, ChinaCollege of Bioengineering, Chongqing University, Chongqing 400044, ChinaAtomic force microscopy (AFM) is an analytical nanotechnology in friction determination between microscale and nanoscale surfaces. AFM has advantages in mechanical measurement, including high sensitivity, resolution, accuracy, and simplicity of operation. This paper will introduce the principles of mechanical measurement by using AFM and reviewing the progress of AFM methods in determining frictions in the field of biochemical science over the past decade. While three friction measurement assays—friction morphology, friction curve and friction process in experimental cases—are mainly introduced, important advances of technology, facilitating future development of AFM are also discussed. In addition to the principles and advances, the authors also give an overview of the shortcomings and restrictions of current AFM methods, and propose potential directions of AFM techniques by combining it with other well-established characterization techniques. AFM methods are expected to see an increase in development and attract wide attention in scientific research.http://www.mdpi.com/2072-666X/9/7/313atomic force microscopy (AFM)frictionbiochemical science |
spellingShingle | Yan Wang Jianhua Wang Friction Determination by Atomic Force Microscopy in Field of Biochemical Science Micromachines atomic force microscopy (AFM) friction biochemical science |
title | Friction Determination by Atomic Force Microscopy in Field of Biochemical Science |
title_full | Friction Determination by Atomic Force Microscopy in Field of Biochemical Science |
title_fullStr | Friction Determination by Atomic Force Microscopy in Field of Biochemical Science |
title_full_unstemmed | Friction Determination by Atomic Force Microscopy in Field of Biochemical Science |
title_short | Friction Determination by Atomic Force Microscopy in Field of Biochemical Science |
title_sort | friction determination by atomic force microscopy in field of biochemical science |
topic | atomic force microscopy (AFM) friction biochemical science |
url | http://www.mdpi.com/2072-666X/9/7/313 |
work_keys_str_mv | AT yanwang frictiondeterminationbyatomicforcemicroscopyinfieldofbiochemicalscience AT jianhuawang frictiondeterminationbyatomicforcemicroscopyinfieldofbiochemicalscience |