Friction Determination by Atomic Force Microscopy in Field of Biochemical Science

Atomic force microscopy (AFM) is an analytical nanotechnology in friction determination between microscale and nanoscale surfaces. AFM has advantages in mechanical measurement, including high sensitivity, resolution, accuracy, and simplicity of operation. This paper will introduce the principles of...

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Main Authors: Yan Wang, Jianhua Wang
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:Micromachines
Subjects:
Online Access:http://www.mdpi.com/2072-666X/9/7/313
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author Yan Wang
Jianhua Wang
author_facet Yan Wang
Jianhua Wang
author_sort Yan Wang
collection DOAJ
description Atomic force microscopy (AFM) is an analytical nanotechnology in friction determination between microscale and nanoscale surfaces. AFM has advantages in mechanical measurement, including high sensitivity, resolution, accuracy, and simplicity of operation. This paper will introduce the principles of mechanical measurement by using AFM and reviewing the progress of AFM methods in determining frictions in the field of biochemical science over the past decade. While three friction measurement assays—friction morphology, friction curve and friction process in experimental cases—are mainly introduced, important advances of technology, facilitating future development of AFM are also discussed. In addition to the principles and advances, the authors also give an overview of the shortcomings and restrictions of current AFM methods, and propose potential directions of AFM techniques by combining it with other well-established characterization techniques. AFM methods are expected to see an increase in development and attract wide attention in scientific research.
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spelling doaj.art-df2fc046714544b48ba2f0a3abc9ba592022-12-21T18:55:21ZengMDPI AGMicromachines2072-666X2018-06-019731310.3390/mi9070313mi9070313Friction Determination by Atomic Force Microscopy in Field of Biochemical ScienceYan Wang0Jianhua Wang1College of Bioengineering, Chongqing University, Chongqing 400044, ChinaCollege of Bioengineering, Chongqing University, Chongqing 400044, ChinaAtomic force microscopy (AFM) is an analytical nanotechnology in friction determination between microscale and nanoscale surfaces. AFM has advantages in mechanical measurement, including high sensitivity, resolution, accuracy, and simplicity of operation. This paper will introduce the principles of mechanical measurement by using AFM and reviewing the progress of AFM methods in determining frictions in the field of biochemical science over the past decade. While three friction measurement assays—friction morphology, friction curve and friction process in experimental cases—are mainly introduced, important advances of technology, facilitating future development of AFM are also discussed. In addition to the principles and advances, the authors also give an overview of the shortcomings and restrictions of current AFM methods, and propose potential directions of AFM techniques by combining it with other well-established characterization techniques. AFM methods are expected to see an increase in development and attract wide attention in scientific research.http://www.mdpi.com/2072-666X/9/7/313atomic force microscopy (AFM)frictionbiochemical science
spellingShingle Yan Wang
Jianhua Wang
Friction Determination by Atomic Force Microscopy in Field of Biochemical Science
Micromachines
atomic force microscopy (AFM)
friction
biochemical science
title Friction Determination by Atomic Force Microscopy in Field of Biochemical Science
title_full Friction Determination by Atomic Force Microscopy in Field of Biochemical Science
title_fullStr Friction Determination by Atomic Force Microscopy in Field of Biochemical Science
title_full_unstemmed Friction Determination by Atomic Force Microscopy in Field of Biochemical Science
title_short Friction Determination by Atomic Force Microscopy in Field of Biochemical Science
title_sort friction determination by atomic force microscopy in field of biochemical science
topic atomic force microscopy (AFM)
friction
biochemical science
url http://www.mdpi.com/2072-666X/9/7/313
work_keys_str_mv AT yanwang frictiondeterminationbyatomicforcemicroscopyinfieldofbiochemicalscience
AT jianhuawang frictiondeterminationbyatomicforcemicroscopyinfieldofbiochemicalscience