Benefits of Metformin Combined with Pemetrexed-Based Platinum Doublets as a First-Line Therapy for Advanced Lung Adenocarcinoma Patients with Diabetes

Benefits of Metformin Combined with Pemetrexed-Based Platinum Doublets as a First-Line Therapy for Advanced Lung Adenocarcinoma Patients with Diabetes

Lung cancer remains a challenge in daily practice. Chemotherapy is first considered for advanced lung adenocarcinoma bearing no active driver mutations. Maintaining drug efficacy and overcoming drug resistance are essential. This study aimed to explore the real-world use of anti-diabetic agent metfo...

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Bibliographic Details
Main Authors: Jiun-Long Wang, Yi-Ting Tsai, Ching-Heng Lin, Abdulkadir Cidem, Theresa Staniczek, Gary Ro-Lin Chang, Chih-Ching Yen, Wei Chen, Kowit-Yu Chong, Chuan-Mu Chen
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Biomolecules
Subjects:
metformin
pemetrexed
lung adenocarcinoma
diabetes
first-line therapy
Online Access:https://www.mdpi.com/2218-273X/11/8/1252

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