Sarcoidosis with bilateral leg lymphedema as the initial presentation: a review of the literature

Sarcoidosis is a granulomatous disease, characterized microscopically by noncaseating granulomas, which may involve multiple organs; however, the lung, skin, and lymph nodes are commonly affected. Sarcoidosis is a great imitator; in the skin, it presents with different cutaneous manifestations inclu...

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Main Authors: Hsin-Wei Huang, Lai-San Wong, Chih-Hung Lee
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2016-03-01
Series:Dermatologica Sinica
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1027811715000464
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author Hsin-Wei Huang
Lai-San Wong
Chih-Hung Lee
author_facet Hsin-Wei Huang
Lai-San Wong
Chih-Hung Lee
author_sort Hsin-Wei Huang
collection DOAJ
description Sarcoidosis is a granulomatous disease, characterized microscopically by noncaseating granulomas, which may involve multiple organs; however, the lung, skin, and lymph nodes are commonly affected. Sarcoidosis is a great imitator; in the skin, it presents with different cutaneous manifestations including lupus pernio, infiltrated plaques, maculopapular eruptions, infiltration of old scars, and subcutaneous sarcoidosis. Lymphedema as an initial presentation is extremely rare; cases are reported in African-American but not Asian patients. Lymphedema associated with sarcoidosis may result from lymphatic obstruction by infiltrating sarcoidosis. We present a case where the symptoms and signs of sarcoidosis were improved after treatment with systemic steroids.
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spelling doaj.art-df36e79c46964c69a7668a75d2e3324f2022-12-21T19:27:44ZengWolters Kluwer Medknow PublicationsDermatologica Sinica1027-81172016-03-01341293210.1016/j.dsi.2015.04.008Sarcoidosis with bilateral leg lymphedema as the initial presentation: a review of the literatureHsin-Wei HuangLai-San WongChih-Hung LeeSarcoidosis is a granulomatous disease, characterized microscopically by noncaseating granulomas, which may involve multiple organs; however, the lung, skin, and lymph nodes are commonly affected. Sarcoidosis is a great imitator; in the skin, it presents with different cutaneous manifestations including lupus pernio, infiltrated plaques, maculopapular eruptions, infiltration of old scars, and subcutaneous sarcoidosis. Lymphedema as an initial presentation is extremely rare; cases are reported in African-American but not Asian patients. Lymphedema associated with sarcoidosis may result from lymphatic obstruction by infiltrating sarcoidosis. We present a case where the symptoms and signs of sarcoidosis were improved after treatment with systemic steroids.http://www.sciencedirect.com/science/article/pii/S1027811715000464lymphedemanoncaseating granulomasarcoidosis
spellingShingle Hsin-Wei Huang
Lai-San Wong
Chih-Hung Lee
Sarcoidosis with bilateral leg lymphedema as the initial presentation: a review of the literature
Dermatologica Sinica
lymphedema
noncaseating granuloma
sarcoidosis
title Sarcoidosis with bilateral leg lymphedema as the initial presentation: a review of the literature
title_full Sarcoidosis with bilateral leg lymphedema as the initial presentation: a review of the literature
title_fullStr Sarcoidosis with bilateral leg lymphedema as the initial presentation: a review of the literature
title_full_unstemmed Sarcoidosis with bilateral leg lymphedema as the initial presentation: a review of the literature
title_short Sarcoidosis with bilateral leg lymphedema as the initial presentation: a review of the literature
title_sort sarcoidosis with bilateral leg lymphedema as the initial presentation a review of the literature
topic lymphedema
noncaseating granuloma
sarcoidosis
url http://www.sciencedirect.com/science/article/pii/S1027811715000464
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AT laisanwong sarcoidosiswithbilateralleglymphedemaastheinitialpresentationareviewoftheliterature
AT chihhunglee sarcoidosiswithbilateralleglymphedemaastheinitialpresentationareviewoftheliterature