Sarcoidosis with bilateral leg lymphedema as the initial presentation: a review of the literature
Sarcoidosis is a granulomatous disease, characterized microscopically by noncaseating granulomas, which may involve multiple organs; however, the lung, skin, and lymph nodes are commonly affected. Sarcoidosis is a great imitator; in the skin, it presents with different cutaneous manifestations inclu...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Wolters Kluwer Medknow Publications
2016-03-01
|
Series: | Dermatologica Sinica |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1027811715000464 |
_version_ | 1818991771322941440 |
---|---|
author | Hsin-Wei Huang Lai-San Wong Chih-Hung Lee |
author_facet | Hsin-Wei Huang Lai-San Wong Chih-Hung Lee |
author_sort | Hsin-Wei Huang |
collection | DOAJ |
description | Sarcoidosis is a granulomatous disease, characterized microscopically by noncaseating granulomas, which may involve multiple organs; however, the lung, skin, and lymph nodes are commonly affected. Sarcoidosis is a great imitator; in the skin, it presents with different cutaneous manifestations including lupus pernio, infiltrated plaques, maculopapular eruptions, infiltration of old scars, and subcutaneous sarcoidosis. Lymphedema as an initial presentation is extremely rare; cases are reported in African-American but not Asian patients. Lymphedema associated with sarcoidosis may result from lymphatic obstruction by infiltrating sarcoidosis. We present a case where the symptoms and signs of sarcoidosis were improved after treatment with systemic steroids. |
first_indexed | 2024-12-20T20:15:34Z |
format | Article |
id | doaj.art-df36e79c46964c69a7668a75d2e3324f |
institution | Directory Open Access Journal |
issn | 1027-8117 |
language | English |
last_indexed | 2024-12-20T20:15:34Z |
publishDate | 2016-03-01 |
publisher | Wolters Kluwer Medknow Publications |
record_format | Article |
series | Dermatologica Sinica |
spelling | doaj.art-df36e79c46964c69a7668a75d2e3324f2022-12-21T19:27:44ZengWolters Kluwer Medknow PublicationsDermatologica Sinica1027-81172016-03-01341293210.1016/j.dsi.2015.04.008Sarcoidosis with bilateral leg lymphedema as the initial presentation: a review of the literatureHsin-Wei HuangLai-San WongChih-Hung LeeSarcoidosis is a granulomatous disease, characterized microscopically by noncaseating granulomas, which may involve multiple organs; however, the lung, skin, and lymph nodes are commonly affected. Sarcoidosis is a great imitator; in the skin, it presents with different cutaneous manifestations including lupus pernio, infiltrated plaques, maculopapular eruptions, infiltration of old scars, and subcutaneous sarcoidosis. Lymphedema as an initial presentation is extremely rare; cases are reported in African-American but not Asian patients. Lymphedema associated with sarcoidosis may result from lymphatic obstruction by infiltrating sarcoidosis. We present a case where the symptoms and signs of sarcoidosis were improved after treatment with systemic steroids.http://www.sciencedirect.com/science/article/pii/S1027811715000464lymphedemanoncaseating granulomasarcoidosis |
spellingShingle | Hsin-Wei Huang Lai-San Wong Chih-Hung Lee Sarcoidosis with bilateral leg lymphedema as the initial presentation: a review of the literature Dermatologica Sinica lymphedema noncaseating granuloma sarcoidosis |
title | Sarcoidosis with bilateral leg lymphedema as the initial presentation: a review of the literature |
title_full | Sarcoidosis with bilateral leg lymphedema as the initial presentation: a review of the literature |
title_fullStr | Sarcoidosis with bilateral leg lymphedema as the initial presentation: a review of the literature |
title_full_unstemmed | Sarcoidosis with bilateral leg lymphedema as the initial presentation: a review of the literature |
title_short | Sarcoidosis with bilateral leg lymphedema as the initial presentation: a review of the literature |
title_sort | sarcoidosis with bilateral leg lymphedema as the initial presentation a review of the literature |
topic | lymphedema noncaseating granuloma sarcoidosis |
url | http://www.sciencedirect.com/science/article/pii/S1027811715000464 |
work_keys_str_mv | AT hsinweihuang sarcoidosiswithbilateralleglymphedemaastheinitialpresentationareviewoftheliterature AT laisanwong sarcoidosiswithbilateralleglymphedemaastheinitialpresentationareviewoftheliterature AT chihhunglee sarcoidosiswithbilateralleglymphedemaastheinitialpresentationareviewoftheliterature |