Role of NADPH Oxidases in Blood–Brain Barrier Disruption and Ischemic Stroke

Role of NADPH Oxidases in Blood–Brain Barrier Disruption and Ischemic Stroke

NADPH oxidases (Nox) are one of the main sources of reactive oxygen species (ROS) in the central nervous system (CNS). While these enzymes have been shown to be involved in physiological regulation of cerebral vascular tone, excessive ROS produced by Nox1-5 play a critical role in blood–brain barrie...

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Bibliographic Details
Main Authors: Marina S. Hernandes, Qian Xu, Kathy K. Griendling
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Antioxidants
Subjects:
NADPH oxidase
blood–brain barrier
ischemic stroke
Online Access:https://www.mdpi.com/2076-3921/11/10/1966

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