Lymphocyte count and A-DROP score in COVID-19 patients: A retrospective observational study
Objectives: To determine the correlation between lymphocyte count and A-DROP score in COVID-19 patients and their role in predicting poor outcomes. Methods: This retrospective observational single-center study was conducted in a tertiary care hospital in Vidisha district, India. COVID-19 patients we...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2022-01-01
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| Series: | Journal of Acute Disease |
| Subjects: | |
| Online Access: | http://www.jadweb.org/article.asp?issn=2221-6189;year=2022;volume=11;issue=3;spage=115;epage=119;aulast=Waikar |
| _version_ | 1811217841806901248 |
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| author | Chandrakant Waikar Vinayak Gour Lal Pranay Sevras Hingwe |
| author_facet | Chandrakant Waikar Vinayak Gour Lal Pranay Sevras Hingwe |
| author_sort | Chandrakant Waikar |
| collection | DOAJ |
| description | Objectives: To determine the correlation between lymphocyte count and A-DROP score in COVID-19 patients and their role in predicting poor outcomes.
Methods: This retrospective observational single-center study was conducted in a tertiary care hospital in Vidisha district, India. COVID-19 patients were included in this study, who were admitted to ICU and the COVID Care Centre from August 2020 to October 2020. Demographic profile, clinical characteristics, medical history, A-DROP score, complete blood counts including lymphocyte counts (on admission), the severity of the disease course, and duration of hospitalization were collected. The correlation between lymphopenia and A-DROP score was determined, and their role in predicting poor outcomes was investigated.
Results: This study included 220 patients, among which 134 were male, and 86 were female [mean age (48.98±16.98) years, 95% CI: 46.72-51.23]. Lymphocyte count in COVID-19 patients negatively correlated with the A-DROP score (r=−0.67, P<0.001). The area under the ROC curve was 0.892 (95% CI: 0.80-0.98, P<0.001) for the lymphocyte count, and the area under the ROC curve was 0.93 (95% CI: 0.84-1.00, P<0.001) for lymphocyte count-A-DROP.
Conclusion: Lymphocyte count along with the A-DROP score on admission could be used to predict the severity of COVID-19 pneumonia and unfavorable outcome. |
| first_indexed | 2024-04-12T07:00:51Z |
| format | Article |
| id | doaj.art-df3afdf7279d4bde9c8568c83ee5983e |
| institution | Directory Open Access Journal |
| issn | 2221-6189 2589-5516 |
| language | English |
| last_indexed | 2024-04-12T07:00:51Z |
| publishDate | 2022-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Acute Disease |
| spelling | doaj.art-df3afdf7279d4bde9c8568c83ee5983e2022-12-22T03:43:01ZengWolters Kluwer Medknow PublicationsJournal of Acute Disease2221-61892589-55162022-01-0111311511910.4103/2221-6189.347779Lymphocyte count and A-DROP score in COVID-19 patients: A retrospective observational studyChandrakant WaikarVinayak GourLal PranaySevras HingweObjectives: To determine the correlation between lymphocyte count and A-DROP score in COVID-19 patients and their role in predicting poor outcomes. Methods: This retrospective observational single-center study was conducted in a tertiary care hospital in Vidisha district, India. COVID-19 patients were included in this study, who were admitted to ICU and the COVID Care Centre from August 2020 to October 2020. Demographic profile, clinical characteristics, medical history, A-DROP score, complete blood counts including lymphocyte counts (on admission), the severity of the disease course, and duration of hospitalization were collected. The correlation between lymphopenia and A-DROP score was determined, and their role in predicting poor outcomes was investigated. Results: This study included 220 patients, among which 134 were male, and 86 were female [mean age (48.98±16.98) years, 95% CI: 46.72-51.23]. Lymphocyte count in COVID-19 patients negatively correlated with the A-DROP score (r=−0.67, P<0.001). The area under the ROC curve was 0.892 (95% CI: 0.80-0.98, P<0.001) for the lymphocyte count, and the area under the ROC curve was 0.93 (95% CI: 0.84-1.00, P<0.001) for lymphocyte count-A-DROP. Conclusion: Lymphocyte count along with the A-DROP score on admission could be used to predict the severity of COVID-19 pneumonia and unfavorable outcome.http://www.jadweb.org/article.asp?issn=2221-6189;year=2022;volume=11;issue=3;spage=115;epage=119;aulast=Waikarcovid-19; pandemic; lymphopenia; pneumonia |
| spellingShingle | Chandrakant Waikar Vinayak Gour Lal Pranay Sevras Hingwe Lymphocyte count and A-DROP score in COVID-19 patients: A retrospective observational study Journal of Acute Disease covid-19; pandemic; lymphopenia; pneumonia |
| title | Lymphocyte count and A-DROP score in COVID-19 patients: A retrospective observational study |
| title_full | Lymphocyte count and A-DROP score in COVID-19 patients: A retrospective observational study |
| title_fullStr | Lymphocyte count and A-DROP score in COVID-19 patients: A retrospective observational study |
| title_full_unstemmed | Lymphocyte count and A-DROP score in COVID-19 patients: A retrospective observational study |
| title_short | Lymphocyte count and A-DROP score in COVID-19 patients: A retrospective observational study |
| title_sort | lymphocyte count and a drop score in covid 19 patients a retrospective observational study |
| topic | covid-19; pandemic; lymphopenia; pneumonia |
| url | http://www.jadweb.org/article.asp?issn=2221-6189;year=2022;volume=11;issue=3;spage=115;epage=119;aulast=Waikar |
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