Implication of Netrin-1 Gain of Expression in Canine Nodal Lymphoma

Implication of Netrin-1 Gain of Expression in Canine Nodal Lymphoma

Netrin-1 is a member of the laminin superfamily, and is known to interact with specific receptors, called dependence receptors. While upon netrin-1 binding these receptors initiate positive signaling, in absence of netrin-1, these receptors trigger apoptosis. Tumor cells can avoid apoptosis by inact...

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Bibliographic Details
Main Authors: Antonin Tortereau, Nadège Milhau, Elodie Rhumy, Marie Castets, Frédérique Ponce, Patrick Mehlen, Thierry Marchal
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Veterinary Sciences
Subjects:
nodal lymphoma
dog
netrin-1
dependence receptors
immunotherapy
Online Access:https://www.mdpi.com/2306-7381/9/9/494

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