Identification of a novel autophagy signature for predicting survival in patients with lung adenocarcinoma

Identification of a novel autophagy signature for predicting survival in patients with lung adenocarcinoma

Background Lung adenocarcinoma (LUAD) is the most commonhistological lung cancer subtype, with an overall five-year survivalrate of only 17%. In this study, we aimed to identify autophagy-related genes (ARGs) and develop an LUAD prognostic signature. Methods In this study, we obtained ARGs from thre...

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Bibliographic Details
Main Authors: Jin Duan, Youming Lei, Guoli Lv, Yinqiang Liu, Wei Zhao, Qingmei Yang, Xiaona Su, Zhijian Song, Leilei Lu, Yunfei Shi
Format: Article
Language:English
Published: PeerJ Inc. 2021-04-01
Series:PeerJ
Subjects:
Lung adenocarcinoma
LASSO Cox regression
The Cancer Genome Atlas
Gene set enrichment analysis
Immune cell analysis
Autophagy
Online Access:https://peerj.com/articles/11074.pdf

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