The Effect of Melatonin Supplement on High Arterial Blood Pressure: An Overview from Clinicaltrials.gov
Ahmed M Ashour Pharmacology and Toxicology Department, College of Pharmacy, Umm Al-Qura University, Makkah, Saudi ArabiaCorrespondence: Ahmed M Ashour, Pharmacology and Toxicology Department, College of Pharmacy, Umm Al-Qura University, Makkah, Saudi Arabia, Tel +966566664464, Fax +966126066693, Ema...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2024-02-01
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| Series: | Journal of Multidisciplinary Healthcare |
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| Online Access: | https://www.dovepress.com/the-effect-of-melatonin-supplement-on-high-arterial-blood-pressure-an--peer-reviewed-fulltext-article-JMDH |
| _version_ | 1797325403565588480 |
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| author | Ashour AM |
| author_facet | Ashour AM |
| author_sort | Ashour AM |
| collection | DOAJ |
| description | Ahmed M Ashour Pharmacology and Toxicology Department, College of Pharmacy, Umm Al-Qura University, Makkah, Saudi ArabiaCorrespondence: Ahmed M Ashour, Pharmacology and Toxicology Department, College of Pharmacy, Umm Al-Qura University, Makkah, Saudi Arabia, Tel +966566664464, Fax +966126066693, Email amashour@uqu.edu.saBackground: Melatonin is a hormone produced by the pineal gland primarily at night. It has been suggested that melatonin may possess various cardiovascular benefits, including the potential to lower blood pressure. For this reason, we sought to identify and provide evidence of the effectiveness of melatonin on high arterial blood pressure in clinical trials.Methods: Using the search term “melatonin and hypertension”, a search of the ClinicalTrials.gov database was performed on October 10th, 2023. I defined the exclusion and inclusion criteria to isolate appropriate clinical trials. Inclusion criteria for the search included hypertension that utilized melatonin as a treatment supplement; all non-related trials were omitted from the search. The data extractions, including study title, study type, study status, and intervention and outcome details, were compiled.Results: Of the 13 clinical trials identified, only three focused on examining the effects of melatonin. The study titles, enrollment numbers, conditions, statuses, interventions, and outcome measures have been explained in depth. Information gathered from these clinical trials will assist us in identifying the possible risks and benefits of melatonin with respect to high arterial blood pressure.Conclusion: Melatonin has been shown to be an effective treatment for lowering blood pressure. More research is required to fully establish the potential benefits and risks and highlight the mechanisms through which melatonin may influence blood pressure regulation.Keywords: melatonin, blood, clinical trials, arterial, supplement |
| first_indexed | 2024-03-08T06:08:59Z |
| format | Article |
| id | doaj.art-df44c39a4dd74ce5849fbf251fa2b9b0 |
| institution | Directory Open Access Journal |
| issn | 1178-2390 |
| language | English |
| last_indexed | 2024-03-08T06:08:59Z |
| publishDate | 2024-02-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Journal of Multidisciplinary Healthcare |
| spelling | doaj.art-df44c39a4dd74ce5849fbf251fa2b9b02024-02-04T17:43:33ZengDove Medical PressJournal of Multidisciplinary Healthcare1178-23902024-02-01Volume 1751752090166The Effect of Melatonin Supplement on High Arterial Blood Pressure: An Overview from Clinicaltrials.govAshour AMAhmed M Ashour Pharmacology and Toxicology Department, College of Pharmacy, Umm Al-Qura University, Makkah, Saudi ArabiaCorrespondence: Ahmed M Ashour, Pharmacology and Toxicology Department, College of Pharmacy, Umm Al-Qura University, Makkah, Saudi Arabia, Tel +966566664464, Fax +966126066693, Email amashour@uqu.edu.saBackground: Melatonin is a hormone produced by the pineal gland primarily at night. It has been suggested that melatonin may possess various cardiovascular benefits, including the potential to lower blood pressure. For this reason, we sought to identify and provide evidence of the effectiveness of melatonin on high arterial blood pressure in clinical trials.Methods: Using the search term “melatonin and hypertension”, a search of the ClinicalTrials.gov database was performed on October 10th, 2023. I defined the exclusion and inclusion criteria to isolate appropriate clinical trials. Inclusion criteria for the search included hypertension that utilized melatonin as a treatment supplement; all non-related trials were omitted from the search. The data extractions, including study title, study type, study status, and intervention and outcome details, were compiled.Results: Of the 13 clinical trials identified, only three focused on examining the effects of melatonin. The study titles, enrollment numbers, conditions, statuses, interventions, and outcome measures have been explained in depth. Information gathered from these clinical trials will assist us in identifying the possible risks and benefits of melatonin with respect to high arterial blood pressure.Conclusion: Melatonin has been shown to be an effective treatment for lowering blood pressure. More research is required to fully establish the potential benefits and risks and highlight the mechanisms through which melatonin may influence blood pressure regulation.Keywords: melatonin, blood, clinical trials, arterial, supplementhttps://www.dovepress.com/the-effect-of-melatonin-supplement-on-high-arterial-blood-pressure-an--peer-reviewed-fulltext-article-JMDHmelatoninbloodclinical trialsarterialsupplement. |
| spellingShingle | Ashour AM The Effect of Melatonin Supplement on High Arterial Blood Pressure: An Overview from Clinicaltrials.gov Journal of Multidisciplinary Healthcare melatonin blood clinical trials arterial supplement. |
| title | The Effect of Melatonin Supplement on High Arterial Blood Pressure: An Overview from Clinicaltrials.gov |
| title_full | The Effect of Melatonin Supplement on High Arterial Blood Pressure: An Overview from Clinicaltrials.gov |
| title_fullStr | The Effect of Melatonin Supplement on High Arterial Blood Pressure: An Overview from Clinicaltrials.gov |
| title_full_unstemmed | The Effect of Melatonin Supplement on High Arterial Blood Pressure: An Overview from Clinicaltrials.gov |
| title_short | The Effect of Melatonin Supplement on High Arterial Blood Pressure: An Overview from Clinicaltrials.gov |
| title_sort | effect of melatonin supplement on high arterial blood pressure an overview from clinicaltrials gov |
| topic | melatonin blood clinical trials arterial supplement. |
| url | https://www.dovepress.com/the-effect-of-melatonin-supplement-on-high-arterial-blood-pressure-an--peer-reviewed-fulltext-article-JMDH |
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