Germ cell tumor: A seven-year experience Children Welfare Teaching Hospital
Background: Germ cell tumors are a rare heterogeneous group of cancers with high cure rates in the pediatric age group. Objectives: To study the clinical and pathological features in a group of patients with germ cell tumors and to evaluate their outcomes. Patients and methods: A record review was u...
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| Format: | Article |
| Language: | English |
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College of Medicine University of Baghdad
2021-07-01
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| Series: | مجلة كلية الطب |
| Subjects: | |
| Online Access: | https://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/1832 |
| _version_ | 1797370384458186752 |
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| author | raghad majid alsaeed Afrah M. Jassim Samaher A. Razaq Mazin F. AL-Jadiry |
| author_facet | raghad majid alsaeed Afrah M. Jassim Samaher A. Razaq Mazin F. AL-Jadiry |
| author_sort | raghad majid alsaeed |
| collection | DOAJ |
| description | Background: Germ cell tumors are a rare heterogeneous group of cancers with high cure rates in the pediatric age group.
Objectives: To study the clinical and pathological features in a group of patients with germ cell tumors and to evaluate their outcomes.
Patients and methods: A record review was undertaken on a group of patients with germ cell tumor who were admitted to the Children Welfare Teaching Hospital in Baghdad during the years 2009 - 2015. Information on gender, age, clinical signs, pathological findings, treatment and overall survival rate were reviewed.
Results: The patients had a mean age of 4.2 years (ranging from 1 month - 14 years). There were 45 girls and 16 boys. Abdominal pain was the most common presentation in 17 patients followed by a lower back mass in 16 patients. Primary sites included extra gonadal (sacrococcygeal 18, pelvis 5, vagina 4, gluteal 3, intra-cardiac, and one each for the mediastinum, orbit and rectum), and gonadal (18 ovarian and 9 testicular). After a mean period of follow-up of 42 months, the overall survival at 1 year was 59%.
Conclusion: The prognosis of children with germ cell tumors is favorable, regardless the site and histopathology. |
| first_indexed | 2024-03-08T18:01:51Z |
| format | Article |
| id | doaj.art-df46969c0a8745baa288d330a7a5edc0 |
| institution | Directory Open Access Journal |
| issn | 0041-9419 2410-8057 |
| language | English |
| last_indexed | 2024-03-08T18:01:51Z |
| publishDate | 2021-07-01 |
| publisher | College of Medicine University of Baghdad |
| record_format | Article |
| series | مجلة كلية الطب |
| spelling | doaj.art-df46969c0a8745baa288d330a7a5edc02024-01-02T01:36:01ZengCollege of Medicine University of Baghdadمجلة كلية الطب0041-94192410-80572021-07-0163210.32007/jfacmedbagdad.6321832Germ cell tumor: A seven-year experience Children Welfare Teaching Hospitalraghad majid alsaeed0Afrah M. Jassim1Samaher A. Razaq2Mazin F. AL-Jadiry3children welfare teaching hospital- hematology centerChildren Welfare Teaching Hospital-Medical City, Pediatric Oncology UnitChildren Welfare Teaching Hospital-Medical City, Pediatric Oncology UnitChildren Welfare Teaching Hospital-Medical City- College of Medicine-University of Baghdad, Pediatric Oncology UnitBackground: Germ cell tumors are a rare heterogeneous group of cancers with high cure rates in the pediatric age group. Objectives: To study the clinical and pathological features in a group of patients with germ cell tumors and to evaluate their outcomes. Patients and methods: A record review was undertaken on a group of patients with germ cell tumor who were admitted to the Children Welfare Teaching Hospital in Baghdad during the years 2009 - 2015. Information on gender, age, clinical signs, pathological findings, treatment and overall survival rate were reviewed. Results: The patients had a mean age of 4.2 years (ranging from 1 month - 14 years). There were 45 girls and 16 boys. Abdominal pain was the most common presentation in 17 patients followed by a lower back mass in 16 patients. Primary sites included extra gonadal (sacrococcygeal 18, pelvis 5, vagina 4, gluteal 3, intra-cardiac, and one each for the mediastinum, orbit and rectum), and gonadal (18 ovarian and 9 testicular). After a mean period of follow-up of 42 months, the overall survival at 1 year was 59%. Conclusion: The prognosis of children with germ cell tumors is favorable, regardless the site and histopathology.https://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/1832Germ cell tumor, Children Welfare Teaching Hospital |
| spellingShingle | raghad majid alsaeed Afrah M. Jassim Samaher A. Razaq Mazin F. AL-Jadiry Germ cell tumor: A seven-year experience Children Welfare Teaching Hospital مجلة كلية الطب Germ cell tumor, Children Welfare Teaching Hospital |
| title | Germ cell tumor: A seven-year experience Children Welfare Teaching Hospital |
| title_full | Germ cell tumor: A seven-year experience Children Welfare Teaching Hospital |
| title_fullStr | Germ cell tumor: A seven-year experience Children Welfare Teaching Hospital |
| title_full_unstemmed | Germ cell tumor: A seven-year experience Children Welfare Teaching Hospital |
| title_short | Germ cell tumor: A seven-year experience Children Welfare Teaching Hospital |
| title_sort | germ cell tumor a seven year experience children welfare teaching hospital |
| topic | Germ cell tumor, Children Welfare Teaching Hospital |
| url | https://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/1832 |
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