Emerging roles for lncRNA-NEAT1 in colorectal cancer
Abstract Colorectal cancer (CRC) is the third cause of cancer death in the world that arises from the glandular and epithelial cells of the large intestine, during a series of genetic or epigenetic alternations. Recently, long non-coding RNAs (lncRNAs) has opened a separate window of research in mol...
| Main Authors: | , , , , , |
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| 格式: | Article |
| 語言: | English |
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BMC
2022-06-01
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| 叢編: | Cancer Cell International |
| 主題: | |
| 在線閱讀: | https://doi.org/10.1186/s12935-022-02627-6 |
| _version_ | 1829116440939069440 |
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| author | Shirin Azizidoost Farhoodeh Ghaedrahmati Omid Anbiyaee Riyadh Ahmad Ali Maryam Cheraghzadeh Maryam Farzaneh |
| author_facet | Shirin Azizidoost Farhoodeh Ghaedrahmati Omid Anbiyaee Riyadh Ahmad Ali Maryam Cheraghzadeh Maryam Farzaneh |
| author_sort | Shirin Azizidoost |
| collection | DOAJ |
| description | Abstract Colorectal cancer (CRC) is the third cause of cancer death in the world that arises from the glandular and epithelial cells of the large intestine, during a series of genetic or epigenetic alternations. Recently, long non-coding RNAs (lncRNAs) has opened a separate window of research in molecular and translational medicine. Emerging evidence has supported that lncRNAs can regulate cell cycle of CRC cells. LncRNA NEAT1 has been verified to participate in colon cancer development and progression. NEAT1 as a competing endogenous RNA could suppress the expression of miRNAs, and then regulate molecules downstream of these miRNAs. In this review, we summarized emerging roles of NEAT1 in CRC cells. |
| first_indexed | 2024-12-12T16:33:54Z |
| format | Article |
| id | doaj.art-df46f21c81c24f989df8d644dbf70c7a |
| institution | Directory Open Access Journal |
| issn | 1475-2867 |
| language | English |
| last_indexed | 2024-12-12T16:33:54Z |
| publishDate | 2022-06-01 |
| publisher | BMC |
| record_format | Article |
| series | Cancer Cell International |
| spelling | doaj.art-df46f21c81c24f989df8d644dbf70c7a2022-12-22T00:18:44ZengBMCCancer Cell International1475-28672022-06-0122111010.1186/s12935-022-02627-6Emerging roles for lncRNA-NEAT1 in colorectal cancerShirin Azizidoost0Farhoodeh Ghaedrahmati1Omid Anbiyaee2Riyadh Ahmad Ali3Maryam Cheraghzadeh4Maryam Farzaneh5Atherosclerosis Research Center, Ahvaz Jundishapur University of Medical SciencesDepartment of Immunology, School of Medicine, Isfahan University of Medical SciencesCardiovascular Research Center, Nemazi Hospital, School of Medicine, Shiraz University of Medical SciencesDepartment of Medical Laboratory Science, College of Health Science, Lebanese French UniversityDepartment of Biochemistry, School of Medicine, Ahvaz Jundishapur University of Medical SciencesFertility, Infertility and Perinatology Research Center, Ahvaz Jundishapur University of Medical SciencesAbstract Colorectal cancer (CRC) is the third cause of cancer death in the world that arises from the glandular and epithelial cells of the large intestine, during a series of genetic or epigenetic alternations. Recently, long non-coding RNAs (lncRNAs) has opened a separate window of research in molecular and translational medicine. Emerging evidence has supported that lncRNAs can regulate cell cycle of CRC cells. LncRNA NEAT1 has been verified to participate in colon cancer development and progression. NEAT1 as a competing endogenous RNA could suppress the expression of miRNAs, and then regulate molecules downstream of these miRNAs. In this review, we summarized emerging roles of NEAT1 in CRC cells.https://doi.org/10.1186/s12935-022-02627-6Colorectal cancerlncRNAsNEAT1Progression |
| spellingShingle | Shirin Azizidoost Farhoodeh Ghaedrahmati Omid Anbiyaee Riyadh Ahmad Ali Maryam Cheraghzadeh Maryam Farzaneh Emerging roles for lncRNA-NEAT1 in colorectal cancer Cancer Cell International Colorectal cancer lncRNAs NEAT1 Progression |
| title | Emerging roles for lncRNA-NEAT1 in colorectal cancer |
| title_full | Emerging roles for lncRNA-NEAT1 in colorectal cancer |
| title_fullStr | Emerging roles for lncRNA-NEAT1 in colorectal cancer |
| title_full_unstemmed | Emerging roles for lncRNA-NEAT1 in colorectal cancer |
| title_short | Emerging roles for lncRNA-NEAT1 in colorectal cancer |
| title_sort | emerging roles for lncrna neat1 in colorectal cancer |
| topic | Colorectal cancer lncRNAs NEAT1 Progression |
| url | https://doi.org/10.1186/s12935-022-02627-6 |
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