Prussian blue nanocubes/carbon nanospheres heterostructure composite for biosensing of metformin

Jagriti Narang,1 Nitesh Malhotra,2 Chaitali Singhal,1 Gajendra Singh,3 Chandra Shekhar Pundir4 1Amity Institute of Nanotechnology, 2Amity Institute of Physiotherapy, Amity University, Noida, Uttar Pradesh, 3Department of Pharmacy, University of Health Sciences, 4Department of Biochemistry, M. D. Un...

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Main Authors: Narang J, Malhotra N, Singhal C, Singh G, Pundir CS
Format: Article
Language:English
Published: Dove Medical Press 2018-03-01
Series:International Journal of Nanomedicine
Subjects:
Online Access:https://www.dovepress.com/prussian-blue-nanocubescarbon-nanospheres-heterostructure-composite-fo-peer-reviewed-article-IJN
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author Narang J
Malhotra N
Singhal C
Singh G
Pundir CS
author_facet Narang J
Malhotra N
Singhal C
Singh G
Pundir CS
author_sort Narang J
collection DOAJ
description Jagriti Narang,1 Nitesh Malhotra,2 Chaitali Singhal,1 Gajendra Singh,3 Chandra Shekhar Pundir4 1Amity Institute of Nanotechnology, 2Amity Institute of Physiotherapy, Amity University, Noida, Uttar Pradesh, 3Department of Pharmacy, University of Health Sciences, 4Department of Biochemistry, M. D. University, Rohtak, Haryana, India Abstract: This paper reports the fabrication of highly sensitive metformin sensor based on Prussian blue (PB) nanocubes/carbon nanosphere (CNS) heterostructures composed of a perfect cube and spherical composite on a fluorine-doped tin oxide surface. Due to the excellent biocompatibility of PB nanocubes the PB/CNS based Mf sensor exhibited a wide linear range of 0.001–10 mM with a response duration of less than 5 s and a detection limit (based on signal to noise ratio) of 0.1 µM. Keywords: metformin, PB nanocubes, carbon nanospheres, sensor, FTO electrode
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spelling doaj.art-df47fd0bd39b41d589653f18a1ca3e6d2022-12-21T19:18:52ZengDove Medical PressInternational Journal of Nanomedicine1178-20132018-03-01Volume 1311712037271Prussian blue nanocubes/carbon nanospheres heterostructure composite for biosensing of metforminNarang JMalhotra NSinghal CSingh GPundir CSJagriti Narang,1 Nitesh Malhotra,2 Chaitali Singhal,1 Gajendra Singh,3 Chandra Shekhar Pundir4 1Amity Institute of Nanotechnology, 2Amity Institute of Physiotherapy, Amity University, Noida, Uttar Pradesh, 3Department of Pharmacy, University of Health Sciences, 4Department of Biochemistry, M. D. University, Rohtak, Haryana, India Abstract: This paper reports the fabrication of highly sensitive metformin sensor based on Prussian blue (PB) nanocubes/carbon nanosphere (CNS) heterostructures composed of a perfect cube and spherical composite on a fluorine-doped tin oxide surface. Due to the excellent biocompatibility of PB nanocubes the PB/CNS based Mf sensor exhibited a wide linear range of 0.001–10 mM with a response duration of less than 5 s and a detection limit (based on signal to noise ratio) of 0.1 µM. Keywords: metformin, PB nanocubes, carbon nanospheres, sensor, FTO electrodehttps://www.dovepress.com/prussian-blue-nanocubescarbon-nanospheres-heterostructure-composite-fo-peer-reviewed-article-IJNMetforminPB nanocubesCarbon nanospheresSensorFTO electrode
spellingShingle Narang J
Malhotra N
Singhal C
Singh G
Pundir CS
Prussian blue nanocubes/carbon nanospheres heterostructure composite for biosensing of metformin
International Journal of Nanomedicine
Metformin
PB nanocubes
Carbon nanospheres
Sensor
FTO electrode
title Prussian blue nanocubes/carbon nanospheres heterostructure composite for biosensing of metformin
title_full Prussian blue nanocubes/carbon nanospheres heterostructure composite for biosensing of metformin
title_fullStr Prussian blue nanocubes/carbon nanospheres heterostructure composite for biosensing of metformin
title_full_unstemmed Prussian blue nanocubes/carbon nanospheres heterostructure composite for biosensing of metformin
title_short Prussian blue nanocubes/carbon nanospheres heterostructure composite for biosensing of metformin
title_sort prussian blue nanocubes carbon nanospheres heterostructure composite for biosensing of metformin
topic Metformin
PB nanocubes
Carbon nanospheres
Sensor
FTO electrode
url https://www.dovepress.com/prussian-blue-nanocubescarbon-nanospheres-heterostructure-composite-fo-peer-reviewed-article-IJN
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