GMEB2 Promotes the Growth of Colorectal Cancer by Activating ADRM1 Transcription and NF-κB Signalling and Is Positively Regulated by the m<sup>6</sup>A Reader YTHDF1

GMEB2 Promotes the Growth of Colorectal Cancer by Activating ADRM1 Transcription and NF-κB Signalling and Is Positively Regulated by the m<sup>6</sup>A Reader YTHDF1

Transcription factors are frequently aberrantly reactivated in various cancers, including colorectal cancer (CRC). However, as a transcription factor, the role of GMEB2 in cancer is still unclear, and further studies are needed. Here, we aimed to identify the function and mechanism of GMEB2 in regul...

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Bibliographic Details
Main Authors: Zhengping Ning, Zhiwei Wu, Fan Zhang, Ming Yang, Zhixing Lu, Bowen Yu, Fei Long, Yihang Guo, Kaiyan Yang, Gui Hu, Yi Zhang, Xiaorong Li, Liang Li, Changwei Lin
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Cancers
Subjects:
colorectal cancer
GMEB2
RNA N6-methyladenosine
YTHDF1
ADRM1
NF-κB
Online Access:https://www.mdpi.com/2072-6694/14/24/6046

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