GREM1/PPP2R3A expression in heterogeneous fibroblasts initiates pulmonary fibrosis

GREM1/PPP2R3A expression in heterogeneous fibroblasts initiates pulmonary fibrosis

Abstract Background Fibroblasts have important roles in the synthesis and remodeling of extracellular matrix (ECM) proteins during pulmonary fibrosis. However, the spatiotemporal distribution of heterogeneous fibroblasts during disease progression remains unknown. Results In the current study, silic...

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Bibliographic Details
Main Authors: Xiaoni Shi, Jing Wang, Xinxin Zhang, Shaoqi Yang, Wei Luo, Sha Wang, Jie Huang, Mengling Chen, Yusi Cheng, Jie Chao
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Cell & Bioscience
Subjects:
Pulmonary fibrosis
Heterogeneous fibroblasts
Single-cell transcriptomics
Spatial transcriptomics
Online Access:https://doi.org/10.1186/s13578-022-00860-0

Internet

https://doi.org/10.1186/s13578-022-00860-0

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