Incidence and risk factors for carbon monoxide poisoning in an emergency department in Nepal
AbstractIncidence of carbon monoxide (CO) poisoning in Nepal has not been studied. The objective of this study was to evaluate baseline carboxyhemoglobin (COHb) concentrations, population risk factors, and incidence of CO poisoning at a single hospital in Nepal. This was a prospective, observational...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2022-12-01
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| Series: | Toxicology Communications |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/24734306.2021.2010955 |
| _version_ | 1797805389657407488 |
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| author | Samita Pant Acharya Andrea Purpura Louise Kao Darlene R. House |
| author_facet | Samita Pant Acharya Andrea Purpura Louise Kao Darlene R. House |
| author_sort | Samita Pant Acharya |
| collection | DOAJ |
| description | AbstractIncidence of carbon monoxide (CO) poisoning in Nepal has not been studied. The objective of this study was to evaluate baseline carboxyhemoglobin (COHb) concentrations, population risk factors, and incidence of CO poisoning at a single hospital in Nepal. This was a prospective, observational study of patients presenting to Patan Hospital Emergency Department from April 2019 to March 2020. Demographics, risk factors for CO poisoning, symptoms, and clinical pretest probability of CO poisoning was documented. COHb concentration was obtained using a noninvasive co-oximeter. Significant CO exposure was defined as COHb concentration > 10%. CO poisoning was defined as COHb > 10% coupled with symptoms. Of 1,040 patients, 745 patients had a recordable COHb concentration. Median age was 40 years (IQR 33) with 407 (55%) females. Average COHb was 7.2%. Warm months were associated with higher COHb concentrations (8.1% vs 6.0%, p < 0.05). Firewood use had higher COHb concentrations compared to gas heating (8.6% vs 7.0%, p < 0.05). Overall, 228 (31%) patients had a COHb concentration > 10% indicating significant CO exposure. Sixteen patients had CO poisoning. We found a significant baseline incidence of COHb > 10% (31%) in patients presenting to a hospital in Nepal. Risk factors for higher baseline COHb concentrations included warm months and cooking with firewood. |
| first_indexed | 2024-03-13T05:51:20Z |
| format | Article |
| id | doaj.art-df56e67599304265a0c34c4ee34672d4 |
| institution | Directory Open Access Journal |
| issn | 2473-4306 |
| language | English |
| last_indexed | 2024-03-13T05:51:20Z |
| publishDate | 2022-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Toxicology Communications |
| spelling | doaj.art-df56e67599304265a0c34c4ee34672d42023-06-13T12:55:24ZengTaylor & Francis GroupToxicology Communications2473-43062022-12-0161131910.1080/24734306.2021.2010955Incidence and risk factors for carbon monoxide poisoning in an emergency department in NepalSamita Pant Acharya0Andrea Purpura1Louise Kao2Darlene R. House3Department of General Practice and Emergency Medicine, Patan Academy of Health Sciences, Patan, NepalDepartment of Emergency Medicine, Indiana University School of Medicine, Indianapolis, IN, USADepartment of Emergency Medicine, Indiana University School of Medicine, Indianapolis, IN, USADepartment of General Practice and Emergency Medicine, Patan Academy of Health Sciences, Patan, NepalAbstractIncidence of carbon monoxide (CO) poisoning in Nepal has not been studied. The objective of this study was to evaluate baseline carboxyhemoglobin (COHb) concentrations, population risk factors, and incidence of CO poisoning at a single hospital in Nepal. This was a prospective, observational study of patients presenting to Patan Hospital Emergency Department from April 2019 to March 2020. Demographics, risk factors for CO poisoning, symptoms, and clinical pretest probability of CO poisoning was documented. COHb concentration was obtained using a noninvasive co-oximeter. Significant CO exposure was defined as COHb concentration > 10%. CO poisoning was defined as COHb > 10% coupled with symptoms. Of 1,040 patients, 745 patients had a recordable COHb concentration. Median age was 40 years (IQR 33) with 407 (55%) females. Average COHb was 7.2%. Warm months were associated with higher COHb concentrations (8.1% vs 6.0%, p < 0.05). Firewood use had higher COHb concentrations compared to gas heating (8.6% vs 7.0%, p < 0.05). Overall, 228 (31%) patients had a COHb concentration > 10% indicating significant CO exposure. Sixteen patients had CO poisoning. We found a significant baseline incidence of COHb > 10% (31%) in patients presenting to a hospital in Nepal. Risk factors for higher baseline COHb concentrations included warm months and cooking with firewood.https://www.tandfonline.com/doi/10.1080/24734306.2021.2010955Carbon monoxide poisoningcarboxyhemoglobinincidencerisk factorsNepal |
| spellingShingle | Samita Pant Acharya Andrea Purpura Louise Kao Darlene R. House Incidence and risk factors for carbon monoxide poisoning in an emergency department in Nepal Toxicology Communications Carbon monoxide poisoning carboxyhemoglobin incidence risk factors Nepal |
| title | Incidence and risk factors for carbon monoxide poisoning in an emergency department in Nepal |
| title_full | Incidence and risk factors for carbon monoxide poisoning in an emergency department in Nepal |
| title_fullStr | Incidence and risk factors for carbon monoxide poisoning in an emergency department in Nepal |
| title_full_unstemmed | Incidence and risk factors for carbon monoxide poisoning in an emergency department in Nepal |
| title_short | Incidence and risk factors for carbon monoxide poisoning in an emergency department in Nepal |
| title_sort | incidence and risk factors for carbon monoxide poisoning in an emergency department in nepal |
| topic | Carbon monoxide poisoning carboxyhemoglobin incidence risk factors Nepal |
| url | https://www.tandfonline.com/doi/10.1080/24734306.2021.2010955 |
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