Constitutive and treatment-induced CXCL8-signalling selectively modulates the efficacy of anti-metabolite therapeutics in metastatic prostate cancer.
BACKGROUND:The current study was undertaken to characterize the effect of anti-metabolites on inducing CXCL8 signaling and determining whether the constitutive and/or drug-induced CXCL8 signaling in metastatic prostate cancer (CaP) cells modulates their sensitivity to this class of agent. METHODS:Th...
Principais autores: | , , , , , |
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Formato: | Artigo |
Idioma: | English |
Publicado em: |
Public Library of Science (PLoS)
2012-01-01
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coleção: | PLoS ONE |
Acesso em linha: | http://europepmc.org/articles/PMC3348872?pdf=render |