Gene flow contributes to diversification of the major fungal pathogen Candida albicans
The fungal pathogen Candida albicans can undergo a parasexual process that may contribute to genetic diversity, but its actual relevance is unclear. Here, Ropars et al. analyse the genomic sequences of 182 C. albicans isolates collected worldwide and find evidence of gene flow and thus parasexuality...
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2018-06-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-018-04787-4 |
| _version_ | 1819129817230999552 |
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| author | Jeanne Ropars Corinne Maufrais Dorothée Diogo Marina Marcet-Houben Aurélie Perin Natacha Sertour Kevin Mosca Emmanuelle Permal Guillaume Laval Christiane Bouchier Laurence Ma Katja Schwartz Kerstin Voelz Robin C. May Julie Poulain Christophe Battail Patrick Wincker Andrew M. Borman Anuradha Chowdhary Shangrong Fan Soo Hyun Kim Patrice Le Pape Orazio Romeo Jong Hee Shin Toni Gabaldon Gavin Sherlock Marie-Elisabeth Bougnoux Christophe d’Enfert |
| author_facet | Jeanne Ropars Corinne Maufrais Dorothée Diogo Marina Marcet-Houben Aurélie Perin Natacha Sertour Kevin Mosca Emmanuelle Permal Guillaume Laval Christiane Bouchier Laurence Ma Katja Schwartz Kerstin Voelz Robin C. May Julie Poulain Christophe Battail Patrick Wincker Andrew M. Borman Anuradha Chowdhary Shangrong Fan Soo Hyun Kim Patrice Le Pape Orazio Romeo Jong Hee Shin Toni Gabaldon Gavin Sherlock Marie-Elisabeth Bougnoux Christophe d’Enfert |
| author_sort | Jeanne Ropars |
| collection | DOAJ |
| description | The fungal pathogen Candida albicans can undergo a parasexual process that may contribute to genetic diversity, but its actual relevance is unclear. Here, Ropars et al. analyse the genomic sequences of 182 C. albicans isolates collected worldwide and find evidence of gene flow and thus parasexuality in nature. |
| first_indexed | 2024-12-22T08:49:44Z |
| format | Article |
| id | doaj.art-df686121e41b41bbbac4e0c33f4eb781 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-22T08:49:44Z |
| publishDate | 2018-06-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-df686121e41b41bbbac4e0c33f4eb7812022-12-21T18:32:00ZengNature PortfolioNature Communications2041-17232018-06-019111010.1038/s41467-018-04787-4Gene flow contributes to diversification of the major fungal pathogen Candida albicansJeanne Ropars0Corinne Maufrais1Dorothée Diogo2Marina Marcet-Houben3Aurélie Perin4Natacha Sertour5Kevin Mosca6Emmanuelle Permal7Guillaume Laval8Christiane Bouchier9Laurence Ma10Katja Schwartz11Kerstin Voelz12Robin C. May13Julie Poulain14Christophe Battail15Patrick Wincker16Andrew M. Borman17Anuradha Chowdhary18Shangrong Fan19Soo Hyun Kim20Patrice Le Pape21Orazio Romeo22Jong Hee Shin23Toni Gabaldon24Gavin Sherlock25Marie-Elisabeth Bougnoux26Christophe d’Enfert27Department of Mycology, Fungal Biology and Pathogenicity Unit, Institut Pasteur, INRADepartment of Mycology, Fungal Biology and Pathogenicity Unit, Institut Pasteur, INRADepartment of Mycology, Fungal Biology and Pathogenicity Unit, Institut Pasteur, INRADepartment of Mycology, Fungal Biology and Pathogenicity Unit, Institut Pasteur, INRADepartment of Mycology, Fungal Biology and Pathogenicity Unit, Institut Pasteur, INRADepartment of Mycology, Fungal Biology and Pathogenicity Unit, Institut Pasteur, INRADepartment of Mycology, Fungal Biology and Pathogenicity Unit, Institut Pasteur, INRADepartment of Mycology, Fungal Biology and Pathogenicity Unit, Institut Pasteur, INRACenter for Bioinformatics, BioStatistics and Integrative Biology (C3BI), USR 3756 IP CNRS, Institut PasteurBiomics Pole, CITECH, Institut PasteurBiomics Pole, CITECH, Institut PasteurDepartment of Genetics, Stanford University Medical SchoolSchool of Biosciences and Institute of Microbiology and Infection, University of BirminghamSchool of Biosciences and Institute of Microbiology and Infection, University of BirminghamCEA, Genoscope, Institut de biologie François JacobCEA, Genoscope, Institut de biologie François JacobCEA, Genoscope, Institut de biologie François JacobUK National Mycology Reference Laboratory, Public Health EnglandDepartment of Medical Mycology, Vallabhbhai Patel Chest Institute, University of DelhiDepartment of Obstetrics and Gynecology, Peking University Shenzhen HospitalDepartment of Laboratory Medicine, Chonnam National University Medical SchoolEA1155 – IICiMed, Institut de Recherche en Santé 2, Université de NantesDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of MessinaDepartment of Laboratory Medicine, Chonnam National University Medical SchoolCentre for Genomic Regulation (CRG), The Barcelona Institute for Science and TechnologyDepartment of Genetics, Stanford University Medical SchoolDepartment of Mycology, Fungal Biology and Pathogenicity Unit, Institut Pasteur, INRADepartment of Mycology, Fungal Biology and Pathogenicity Unit, Institut Pasteur, INRAThe fungal pathogen Candida albicans can undergo a parasexual process that may contribute to genetic diversity, but its actual relevance is unclear. Here, Ropars et al. analyse the genomic sequences of 182 C. albicans isolates collected worldwide and find evidence of gene flow and thus parasexuality in nature.https://doi.org/10.1038/s41467-018-04787-4 |
| spellingShingle | Jeanne Ropars Corinne Maufrais Dorothée Diogo Marina Marcet-Houben Aurélie Perin Natacha Sertour Kevin Mosca Emmanuelle Permal Guillaume Laval Christiane Bouchier Laurence Ma Katja Schwartz Kerstin Voelz Robin C. May Julie Poulain Christophe Battail Patrick Wincker Andrew M. Borman Anuradha Chowdhary Shangrong Fan Soo Hyun Kim Patrice Le Pape Orazio Romeo Jong Hee Shin Toni Gabaldon Gavin Sherlock Marie-Elisabeth Bougnoux Christophe d’Enfert Gene flow contributes to diversification of the major fungal pathogen Candida albicans Nature Communications |
| title | Gene flow contributes to diversification of the major fungal pathogen Candida albicans |
| title_full | Gene flow contributes to diversification of the major fungal pathogen Candida albicans |
| title_fullStr | Gene flow contributes to diversification of the major fungal pathogen Candida albicans |
| title_full_unstemmed | Gene flow contributes to diversification of the major fungal pathogen Candida albicans |
| title_short | Gene flow contributes to diversification of the major fungal pathogen Candida albicans |
| title_sort | gene flow contributes to diversification of the major fungal pathogen candida albicans |
| url | https://doi.org/10.1038/s41467-018-04787-4 |
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