Data-driven reduction of dendritic morphologies with preserved dendro-somatic responses

Dendrites shape information flow in neurons. Yet, there is little consensus on the level of spatial complexity at which they operate. Through carefully chosen parameter fits, solvable in the least-squares sense, we obtain accurate reduced compartmental models at any level of complexity. We show that...

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Bibliographic Details
Main Authors: Willem AM Wybo, Jakob Jordan, Benjamin Ellenberger, Ulisses Marti Mengual, Thomas Nevian, Walter Senn
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-01-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/60936