ETIOLOGY AND NEUROLOGICAL COMPLICATIONS OF BACTERIAL MENINGITIS IN 189 PATIENTS

Results of a seven year (April 1985 to March 1992) prospoective study of bacterial meningitis in 189 infants and children admitted to our Center indicate that: 1) Tiie Gram-negative bacilli, especially Klebsiella species, are the leading cause of bacterial meningitis in neonates and young infants (&...

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Main Authors: P. Tabatabaie ., S. Sayahtaheri., A. Siadati O. Alizad
Format: Article
Language:English
Published: Tehran University of Medical Sciences 1997-06-01
Series:Acta Medica Iranica
Subjects:
Online Access:http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/4943.pdf&manuscript_id=4943
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author P. Tabatabaie .
S. Sayahtaheri.
A. Siadati O. Alizad
author_facet P. Tabatabaie .
S. Sayahtaheri.
A. Siadati O. Alizad
author_sort P. Tabatabaie .
collection DOAJ
description Results of a seven year (April 1985 to March 1992) prospoective study of bacterial meningitis in 189 infants and children admitted to our Center indicate that: 1) Tiie Gram-negative bacilli, especially Klebsiella species, are the leading cause of bacterial meningitis in neonates and young infants (<2 months), group B Streptococcus meningitis is rare, and Listeria monocytogenes meningitis is not observed. 2) Haemophilus influenzae is the leading cause of bacterial meningitis in children under 4 years old and Streptococcus pneumoniae becomes the leading cause over 5 years old. 3) Nine percent of H. influenzae isolates were ampicillin - resistant and 5% of S. pneumoniae were penicillin G resistant. All but one Niesseria meningitidis isolates were penicillin - susceptible. Both penicillin G f chloramphenicol or ampicillin/chloramphenicol resistance among these isolates were 2 percent. 4) The neurological compilations and mortality were highest under two months of age, 39% of these neonates died due to complications as compared to 22% in all other age groups combined. 5) Dexamethasone improves outcome when used as an adjunctive therapy for bacterial meningitis in infants and children. Tlie immediate and long-term clinical profiles both indicate better outcomes for dexamethasone.
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spelling doaj.art-df6d50f9a84c479e9aa9e226f4de48ec2022-12-21T21:21:29ZengTehran University of Medical SciencesActa Medica Iranica0044-60251997-06-01351-23338ETIOLOGY AND NEUROLOGICAL COMPLICATIONS OF BACTERIAL MENINGITIS IN 189 PATIENTSP. Tabatabaie .S. Sayahtaheri.A. Siadati O. AlizadResults of a seven year (April 1985 to March 1992) prospoective study of bacterial meningitis in 189 infants and children admitted to our Center indicate that: 1) Tiie Gram-negative bacilli, especially Klebsiella species, are the leading cause of bacterial meningitis in neonates and young infants (<2 months), group B Streptococcus meningitis is rare, and Listeria monocytogenes meningitis is not observed. 2) Haemophilus influenzae is the leading cause of bacterial meningitis in children under 4 years old and Streptococcus pneumoniae becomes the leading cause over 5 years old. 3) Nine percent of H. influenzae isolates were ampicillin - resistant and 5% of S. pneumoniae were penicillin G resistant. All but one Niesseria meningitidis isolates were penicillin - susceptible. Both penicillin G f chloramphenicol or ampicillin/chloramphenicol resistance among these isolates were 2 percent. 4) The neurological compilations and mortality were highest under two months of age, 39% of these neonates died due to complications as compared to 22% in all other age groups combined. 5) Dexamethasone improves outcome when used as an adjunctive therapy for bacterial meningitis in infants and children. Tlie immediate and long-term clinical profiles both indicate better outcomes for dexamethasone.http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/4943.pdf&manuscript_id=4943etiological agentsempirical therapyneurological complications
spellingShingle P. Tabatabaie .
S. Sayahtaheri.
A. Siadati O. Alizad
ETIOLOGY AND NEUROLOGICAL COMPLICATIONS OF BACTERIAL MENINGITIS IN 189 PATIENTS
Acta Medica Iranica
etiological agents
empirical therapy
neurological complications
title ETIOLOGY AND NEUROLOGICAL COMPLICATIONS OF BACTERIAL MENINGITIS IN 189 PATIENTS
title_full ETIOLOGY AND NEUROLOGICAL COMPLICATIONS OF BACTERIAL MENINGITIS IN 189 PATIENTS
title_fullStr ETIOLOGY AND NEUROLOGICAL COMPLICATIONS OF BACTERIAL MENINGITIS IN 189 PATIENTS
title_full_unstemmed ETIOLOGY AND NEUROLOGICAL COMPLICATIONS OF BACTERIAL MENINGITIS IN 189 PATIENTS
title_short ETIOLOGY AND NEUROLOGICAL COMPLICATIONS OF BACTERIAL MENINGITIS IN 189 PATIENTS
title_sort etiology and neurological complications of bacterial meningitis in 189 patients
topic etiological agents
empirical therapy
neurological complications
url http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/4943.pdf&manuscript_id=4943
work_keys_str_mv AT ptabatabaie etiologyandneurologicalcomplicationsofbacterialmeningitisin189patients
AT ssayahtaheri etiologyandneurologicalcomplicationsofbacterialmeningitisin189patients
AT asiadatioalizad etiologyandneurologicalcomplicationsofbacterialmeningitisin189patients