Sonophotodynamic Inactivation: The power of light and ultrasound in the battle against microorganisms
The inactivation of pathogenic microorganisms that are a threat to the human being is an old challenge that needs to be overcome, mainly because microorganisms are able to develop resistance that leads to the failure of the treatment. Moreover, the biofilm living form is a complex microorganism comm...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2021-09-01
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| Series: | Journal of Photochemistry and Photobiology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666469021000245 |
| _version_ | 1818458155748687872 |
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| author | Fernanda Alves Erika Toneth Ponce Ayala Sebastião Pratavieira |
| author_facet | Fernanda Alves Erika Toneth Ponce Ayala Sebastião Pratavieira |
| author_sort | Fernanda Alves |
| collection | DOAJ |
| description | The inactivation of pathogenic microorganisms that are a threat to the human being is an old challenge that needs to be overcome, mainly because microorganisms are able to develop resistance that leads to the failure of the treatment. Moreover, the biofilm living form is a complex microorganism community that is less susceptible to antimicrobials agents. For this reason, the search for alternative therapies that are not able to induce resistance and have the ability to inactivate the biofilms is unquestionably needed. In this review, Photodynamic and Sonodynamic Inactivation (PDI and SDI) are suggested as promising antimicrobial approaches. However, the use of the combined therapy, called Sonophotodynamic Inactivation (SPDI), is reinforced and encouraged for microbial diseases. As long as SPDI has been demonstrated to be more effective in inactivating microorganisms than PDI and SDI, it is allowed to reduce the time and parameters of the treatment, turning this therapy safer for mammalian cells. |
| first_indexed | 2024-12-14T22:53:58Z |
| format | Article |
| id | doaj.art-df7043369c084d11aa717c0be20f9265 |
| institution | Directory Open Access Journal |
| issn | 2666-4690 |
| language | English |
| last_indexed | 2024-12-14T22:53:58Z |
| publishDate | 2021-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Photochemistry and Photobiology |
| spelling | doaj.art-df7043369c084d11aa717c0be20f92652022-12-21T22:44:38ZengElsevierJournal of Photochemistry and Photobiology2666-46902021-09-017100039Sonophotodynamic Inactivation: The power of light and ultrasound in the battle against microorganismsFernanda Alves0Erika Toneth Ponce Ayala1Sebastião Pratavieira2Corresponding author at: Av. Trabalhador São-carlense, 400, Centro, CEP 13560-970, São Carlos, SP, Brazil.; São Carlos Institute of Physics, University of São Paulo, PO Box 369, 13560-970, São Carlos, SP, BrazilSão Carlos Institute of Physics, University of São Paulo, PO Box 369, 13560-970, São Carlos, SP, BrazilSão Carlos Institute of Physics, University of São Paulo, PO Box 369, 13560-970, São Carlos, SP, BrazilThe inactivation of pathogenic microorganisms that are a threat to the human being is an old challenge that needs to be overcome, mainly because microorganisms are able to develop resistance that leads to the failure of the treatment. Moreover, the biofilm living form is a complex microorganism community that is less susceptible to antimicrobials agents. For this reason, the search for alternative therapies that are not able to induce resistance and have the ability to inactivate the biofilms is unquestionably needed. In this review, Photodynamic and Sonodynamic Inactivation (PDI and SDI) are suggested as promising antimicrobial approaches. However, the use of the combined therapy, called Sonophotodynamic Inactivation (SPDI), is reinforced and encouraged for microbial diseases. As long as SPDI has been demonstrated to be more effective in inactivating microorganisms than PDI and SDI, it is allowed to reduce the time and parameters of the treatment, turning this therapy safer for mammalian cells.http://www.sciencedirect.com/science/article/pii/S2666469021000245Photodynamic inactivationSonodynamic inactivationSonophotodynamic inactivationUltrasoundAntimicrobial resistance |
| spellingShingle | Fernanda Alves Erika Toneth Ponce Ayala Sebastião Pratavieira Sonophotodynamic Inactivation: The power of light and ultrasound in the battle against microorganisms Journal of Photochemistry and Photobiology Photodynamic inactivation Sonodynamic inactivation Sonophotodynamic inactivation Ultrasound Antimicrobial resistance |
| title | Sonophotodynamic Inactivation: The power of light and ultrasound in the battle against microorganisms |
| title_full | Sonophotodynamic Inactivation: The power of light and ultrasound in the battle against microorganisms |
| title_fullStr | Sonophotodynamic Inactivation: The power of light and ultrasound in the battle against microorganisms |
| title_full_unstemmed | Sonophotodynamic Inactivation: The power of light and ultrasound in the battle against microorganisms |
| title_short | Sonophotodynamic Inactivation: The power of light and ultrasound in the battle against microorganisms |
| title_sort | sonophotodynamic inactivation the power of light and ultrasound in the battle against microorganisms |
| topic | Photodynamic inactivation Sonodynamic inactivation Sonophotodynamic inactivation Ultrasound Antimicrobial resistance |
| url | http://www.sciencedirect.com/science/article/pii/S2666469021000245 |
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