Experience of implantation of flow-diverter in the acute period of aneurismatic intracranial hemorrhage

In the period from 2013 to 2019 at the Scientific and Practical Center for Endovascular Neuroradiology of the National Academy of Medical Sciences of Ukraine, implantation of flow-diverter in the acute period of aneurysmal intracranial hemorrhage was performed in six patients (4 (66.7 %) men and 2 (...

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Main Authors: D.V. Shchehlov, O.A. Pastushyn, O.E. Svyrydiuk, S.V. Konotopchik, A.V. Naida
Format: Article
Language:English
Published: Allukrainian Association of Endovascular Neuroradiology 2020-01-01
Series:Ендоваскулярна нейрорентгенохірургія
Subjects:
Online Access:https://enj.org.ua/index.php/journal/article/view/121
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author D.V. Shchehlov
O.A. Pastushyn
O.E. Svyrydiuk
S.V. Konotopchik
A.V. Naida
author_facet D.V. Shchehlov
O.A. Pastushyn
O.E. Svyrydiuk
S.V. Konotopchik
A.V. Naida
author_sort D.V. Shchehlov
collection DOAJ
description In the period from 2013 to 2019 at the Scientific and Practical Center for Endovascular Neuroradiology of the National Academy of Medical Sciences of Ukraine, implantation of flow-diverter in the acute period of aneurysmal intracranial hemorrhage was performed in six patients (4 (66.7 %) men and 2 (33.3 %) women. The average age was 50 years). Hemorrhage was diagnosed using multispiral computed tomography, aneurysm was verified using cerebral subtraction angiography according to Seldinger. In 3 cases the aneurysm was located on the internal carotid artery, in 2 cases – on V4-segment of the vertebral artery, in1 case – on A1-segment of the anterior cerebral artery. Five patients received a loading dose of double antiplatelet therapy before implantation of a flow-diverter (300 mg clopidogrel and 300 mg acetylsalicylic acid). One patient received dual antiplatelet therapy (75 mg clopidogrel and 75 mg acetylsalicylic acid) in five days before stent implantation. All patients after implantation of a flow-diverter received double antiplatelet therapy in a standard dose (75 mg clopidogrel and 75 mg acetylsalicylic acid). In five cases a FRED (Microvention - Terumo) flow-diverter was used and in one case – Pipeline (Medtronic). The diameter and length of the stent depended on the angioantomy of the aneurysm and the bearing artery. In two cases the implantation of a flow-diverter was accompanied by the implantation of micro coils into the cavity of the aneurysm, in four cases – as a single endovascular treatment technique. There were no complications in the early or late postoperative period. At the time of discharge on the Glasgow modified exit scale (GOSE) five patients had more than 5 points, one patient died (1 point) for reasons not related to the underlying disease. A control examination in the period from 6 to 12 month after implantation passed three patients, in all cases of aneurysm from the blood circulation is totally excluded.
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spelling doaj.art-df72fa7107a947f0931a03db5518af7f2022-12-21T19:11:23ZengAllukrainian Association of Endovascular NeuroradiologyЕндоваскулярна нейрорентгенохірургія2304-93592663-69642020-01-01293546210.26683/2304-9359-2019-3(29)-54-62121Experience of implantation of flow-diverter in the acute period of aneurismatic intracranial hemorrhageD.V. Shchehlov0O.A. Pastushyn1O.E. Svyrydiuk2S.V. Konotopchik3A.V. Naida4SO «Scientific-practical Center of endovascular neuroradiology NAMS of Ukraine», KyivSO «Scientific-practical Center of endovascular neuroradiology NAMS of Ukraine», KyivSO «Scientific-practical Center of endovascular neuroradiology NAMS of Ukraine», KyivSO «Scientific-practical Center of endovascular neuroradiology NAMS of Ukraine», KyivSO «Scientific-practical Center of endovascular neuroradiology NAMS of Ukraine», KyivIn the period from 2013 to 2019 at the Scientific and Practical Center for Endovascular Neuroradiology of the National Academy of Medical Sciences of Ukraine, implantation of flow-diverter in the acute period of aneurysmal intracranial hemorrhage was performed in six patients (4 (66.7 %) men and 2 (33.3 %) women. The average age was 50 years). Hemorrhage was diagnosed using multispiral computed tomography, aneurysm was verified using cerebral subtraction angiography according to Seldinger. In 3 cases the aneurysm was located on the internal carotid artery, in 2 cases – on V4-segment of the vertebral artery, in1 case – on A1-segment of the anterior cerebral artery. Five patients received a loading dose of double antiplatelet therapy before implantation of a flow-diverter (300 mg clopidogrel and 300 mg acetylsalicylic acid). One patient received dual antiplatelet therapy (75 mg clopidogrel and 75 mg acetylsalicylic acid) in five days before stent implantation. All patients after implantation of a flow-diverter received double antiplatelet therapy in a standard dose (75 mg clopidogrel and 75 mg acetylsalicylic acid). In five cases a FRED (Microvention - Terumo) flow-diverter was used and in one case – Pipeline (Medtronic). The diameter and length of the stent depended on the angioantomy of the aneurysm and the bearing artery. In two cases the implantation of a flow-diverter was accompanied by the implantation of micro coils into the cavity of the aneurysm, in four cases – as a single endovascular treatment technique. There were no complications in the early or late postoperative period. At the time of discharge on the Glasgow modified exit scale (GOSE) five patients had more than 5 points, one patient died (1 point) for reasons not related to the underlying disease. A control examination in the period from 6 to 12 month after implantation passed three patients, in all cases of aneurysm from the blood circulation is totally excluded.https://enj.org.ua/index.php/journal/article/view/121stroke; cerebral angiography; aneurysm; flow-diverter stent; hemorrhage; neurosurgery.
spellingShingle D.V. Shchehlov
O.A. Pastushyn
O.E. Svyrydiuk
S.V. Konotopchik
A.V. Naida
Experience of implantation of flow-diverter in the acute period of aneurismatic intracranial hemorrhage
Ендоваскулярна нейрорентгенохірургія
stroke; cerebral angiography; aneurysm; flow-diverter stent; hemorrhage; neurosurgery.
title Experience of implantation of flow-diverter in the acute period of aneurismatic intracranial hemorrhage
title_full Experience of implantation of flow-diverter in the acute period of aneurismatic intracranial hemorrhage
title_fullStr Experience of implantation of flow-diverter in the acute period of aneurismatic intracranial hemorrhage
title_full_unstemmed Experience of implantation of flow-diverter in the acute period of aneurismatic intracranial hemorrhage
title_short Experience of implantation of flow-diverter in the acute period of aneurismatic intracranial hemorrhage
title_sort experience of implantation of flow diverter in the acute period of aneurismatic intracranial hemorrhage
topic stroke; cerebral angiography; aneurysm; flow-diverter stent; hemorrhage; neurosurgery.
url https://enj.org.ua/index.php/journal/article/view/121
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AT oesvyrydiuk experienceofimplantationofflowdiverterintheacuteperiodofaneurismaticintracranialhemorrhage
AT svkonotopchik experienceofimplantationofflowdiverterintheacuteperiodofaneurismaticintracranialhemorrhage
AT avnaida experienceofimplantationofflowdiverterintheacuteperiodofaneurismaticintracranialhemorrhage