NEW APPROACH IN URTICARIA TREATMENT
The article presents the European Guidelines for the Diagnostics and Management of Urticaria (revised in 2013) and new data on the physiopathology of urticaria related to the role of the platelet-activating factor (PAF) activating mast cells, attracting eosinophils and neutrophils, improving vascula...
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| Format: | Article |
| Language: | English |
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State Scientific Center of Dermatovenereology and Cosmetology
2017-08-01
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| Series: | Vestnik Dermatologii i Venerologii |
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| Online Access: | https://www.vestnikdv.ru/jour/article/view/95 |
| _version_ | 1827846911810338816 |
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| author | A. V. Samtsov |
| author_facet | A. V. Samtsov |
| author_sort | A. V. Samtsov |
| collection | DOAJ |
| description | The article presents the European Guidelines for the Diagnostics and Management of Urticaria (revised in 2013) and new data on the physiopathology of urticaria related to the role of the platelet-activating factor (PAF) activating mast cells, attracting eosinophils and neutrophils, improving vascular permeability (it is more potent than histamine by 1,000 times) and mucosal edema, and increasing the level of pro-inflammatory cytokines. The data promoted the creation of a new rupatadine molecule, which blocks histamine and PAF receptors at the same time improving the therapeutic effect during urticaria treatment as compared to other antihistamine drugs. The author presents the study results confirming the efficacy and safety of rupatadine. |
| first_indexed | 2024-03-12T09:23:41Z |
| format | Article |
| id | doaj.art-df75050b4fa2423c926043a61c9351d2 |
| institution | Directory Open Access Journal |
| issn | 0042-4609 2313-6294 |
| language | English |
| last_indexed | 2024-03-12T09:23:41Z |
| publishDate | 2017-08-01 |
| publisher | State Scientific Center of Dermatovenereology and Cosmetology |
| record_format | Article |
| series | Vestnik Dermatologii i Venerologii |
| spelling | doaj.art-df75050b4fa2423c926043a61c9351d22023-09-02T14:23:30ZengState Scientific Center of Dermatovenereology and CosmetologyVestnik Dermatologii i Venerologii0042-46092313-62942017-08-010615816210.25208/0042-4609-2014-0-6-158-16294NEW APPROACH IN URTICARIA TREATMENTA. V. Samtsov0Military Medical Academy named after S.M. Kirov Ministry of Defense of the Russian FederationThe article presents the European Guidelines for the Diagnostics and Management of Urticaria (revised in 2013) and new data on the physiopathology of urticaria related to the role of the platelet-activating factor (PAF) activating mast cells, attracting eosinophils and neutrophils, improving vascular permeability (it is more potent than histamine by 1,000 times) and mucosal edema, and increasing the level of pro-inflammatory cytokines. The data promoted the creation of a new rupatadine molecule, which blocks histamine and PAF receptors at the same time improving the therapeutic effect during urticaria treatment as compared to other antihistamine drugs. The author presents the study results confirming the efficacy and safety of rupatadine.https://www.vestnikdv.ru/jour/article/view/95крапивницарекомендациирупатадинurticariarecommendationsrupatadine |
| spellingShingle | A. V. Samtsov NEW APPROACH IN URTICARIA TREATMENT Vestnik Dermatologii i Venerologii крапивница рекомендации рупатадин urticaria recommendations rupatadine |
| title | NEW APPROACH IN URTICARIA TREATMENT |
| title_full | NEW APPROACH IN URTICARIA TREATMENT |
| title_fullStr | NEW APPROACH IN URTICARIA TREATMENT |
| title_full_unstemmed | NEW APPROACH IN URTICARIA TREATMENT |
| title_short | NEW APPROACH IN URTICARIA TREATMENT |
| title_sort | new approach in urticaria treatment |
| topic | крапивница рекомендации рупатадин urticaria recommendations rupatadine |
| url | https://www.vestnikdv.ru/jour/article/view/95 |
| work_keys_str_mv | AT avsamtsov newapproachinurticariatreatment |