hnRNPM induces translation switch under hypoxia to promote colon cancer developmentResearch in Context
Background: Hypoxia suppresses global protein production, yet certain essential proteins are translated through alternative pathways to survive under hypoxic stress. Translation via the internal ribosome entry site (IRES) is a means to produce proteins under stress conditions such as hypoxia; howeve...
Main Authors: | Tsung-Ming Chen, Ming-Chih Lai, Yi-Han Li, Ya-Ling Chan, Chih-Hao Wu, Yu-Ming Wang, Chun-Wei Chien, San-Yuan Huang, H. Sunny Sun, Shaw-Jenq Tsai |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-03-01
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Series: | EBioMedicine |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2352396419301380 |
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