A Phytophthora receptor-like kinase regulates oospore development and can activate pattern-triggered plant immunity
Abstract Plant cell-surface leucine-rich repeat receptor-like kinases (LRR-RLKs) and receptor-like proteins (LRR-RLPs) form dynamic complexes to receive a variety of extracellular signals. LRR-RLKs are also widespread in oomycete pathogens, whereas it remains enigmatic whether plant and oomycete LRR...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2023-07-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-023-40171-7 |
| _version_ | 1797752728370282496 |
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| author | Yong Pei Peiyun Ji Jierui Si Hanqing Zhao Sicong Zhang Ruofei Xu Huijun Qiao Weiwei Duan Danyu Shen Zhiyuan Yin Daolong Dou |
| author_facet | Yong Pei Peiyun Ji Jierui Si Hanqing Zhao Sicong Zhang Ruofei Xu Huijun Qiao Weiwei Duan Danyu Shen Zhiyuan Yin Daolong Dou |
| author_sort | Yong Pei |
| collection | DOAJ |
| description | Abstract Plant cell-surface leucine-rich repeat receptor-like kinases (LRR-RLKs) and receptor-like proteins (LRR-RLPs) form dynamic complexes to receive a variety of extracellular signals. LRR-RLKs are also widespread in oomycete pathogens, whereas it remains enigmatic whether plant and oomycete LRR-RLKs could mediate cell-to-cell communications between pathogen and host. Here, we report that an LRR-RLK from the soybean root and stem rot pathogen Phytophthora sojae, PsRLK6, can activate typical pattern-triggered immunity in host soybean and nonhost tomato and Nicotiana benthamiana plants. PsRLK6 homologs are conserved in oomycetes and also exhibit immunity-inducing activity. A small region (LRR5-6) in the extracellular domain of PsRLK6 is sufficient to activate BAK1- and SOBIR1-dependent immune responses, suggesting that PsRLK6 is likely recognized by a plant LRR-RLP. Moreover, PsRLK6 is shown to be up-regulated during oospore maturation and essential for the oospore development of P. sojae. Our data provide a novel type of microbe-associated molecular pattern that functions in the sexual reproduction of oomycete, and a scenario in which a pathogen LRR-RLK could be sensed by a plant LRR-RLP to mount plant immunity. |
| first_indexed | 2024-03-12T17:07:37Z |
| format | Article |
| id | doaj.art-df76d22657154f639040f89a9ad5d986 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-03-12T17:07:37Z |
| publishDate | 2023-07-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-df76d22657154f639040f89a9ad5d9862023-08-06T11:19:52ZengNature PortfolioNature Communications2041-17232023-07-0114111510.1038/s41467-023-40171-7A Phytophthora receptor-like kinase regulates oospore development and can activate pattern-triggered plant immunityYong Pei0Peiyun Ji1Jierui Si2Hanqing Zhao3Sicong Zhang4Ruofei Xu5Huijun Qiao6Weiwei Duan7Danyu Shen8Zhiyuan Yin9Daolong Dou10College of Plant Protection, Nanjing Agricultural UniversityCollege of Plant Protection, Nanjing Agricultural UniversityCollege of Plant Protection, Nanjing Agricultural UniversityCollege of Plant Protection, Nanjing Agricultural UniversityCollege of Plant Protection, Nanjing Agricultural UniversityCollege of Plant Protection, Nanjing Agricultural UniversityCollege of Plant Protection, Nanjing Agricultural UniversityCollege of Plant Protection, Nanjing Agricultural UniversityCollege of Plant Protection, Nanjing Agricultural UniversityCollege of Plant Protection, Nanjing Agricultural UniversityCollege of Plant Protection, Nanjing Agricultural UniversityAbstract Plant cell-surface leucine-rich repeat receptor-like kinases (LRR-RLKs) and receptor-like proteins (LRR-RLPs) form dynamic complexes to receive a variety of extracellular signals. LRR-RLKs are also widespread in oomycete pathogens, whereas it remains enigmatic whether plant and oomycete LRR-RLKs could mediate cell-to-cell communications between pathogen and host. Here, we report that an LRR-RLK from the soybean root and stem rot pathogen Phytophthora sojae, PsRLK6, can activate typical pattern-triggered immunity in host soybean and nonhost tomato and Nicotiana benthamiana plants. PsRLK6 homologs are conserved in oomycetes and also exhibit immunity-inducing activity. A small region (LRR5-6) in the extracellular domain of PsRLK6 is sufficient to activate BAK1- and SOBIR1-dependent immune responses, suggesting that PsRLK6 is likely recognized by a plant LRR-RLP. Moreover, PsRLK6 is shown to be up-regulated during oospore maturation and essential for the oospore development of P. sojae. Our data provide a novel type of microbe-associated molecular pattern that functions in the sexual reproduction of oomycete, and a scenario in which a pathogen LRR-RLK could be sensed by a plant LRR-RLP to mount plant immunity.https://doi.org/10.1038/s41467-023-40171-7 |
| spellingShingle | Yong Pei Peiyun Ji Jierui Si Hanqing Zhao Sicong Zhang Ruofei Xu Huijun Qiao Weiwei Duan Danyu Shen Zhiyuan Yin Daolong Dou A Phytophthora receptor-like kinase regulates oospore development and can activate pattern-triggered plant immunity Nature Communications |
| title | A Phytophthora receptor-like kinase regulates oospore development and can activate pattern-triggered plant immunity |
| title_full | A Phytophthora receptor-like kinase regulates oospore development and can activate pattern-triggered plant immunity |
| title_fullStr | A Phytophthora receptor-like kinase regulates oospore development and can activate pattern-triggered plant immunity |
| title_full_unstemmed | A Phytophthora receptor-like kinase regulates oospore development and can activate pattern-triggered plant immunity |
| title_short | A Phytophthora receptor-like kinase regulates oospore development and can activate pattern-triggered plant immunity |
| title_sort | phytophthora receptor like kinase regulates oospore development and can activate pattern triggered plant immunity |
| url | https://doi.org/10.1038/s41467-023-40171-7 |
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