Geographical Distribution of Genetic Variants and Lineages of SARS-CoV-2 in Chile

The pandemic caused by the new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a worldwide public health concern. First confined in China and then disseminated widely across Europe and America, SARS-CoV-2 has impacted and moved the scientific community around the world to working in...

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Main Authors: Andrés E. Castillo, Bárbara Parra, Paz Tapia, Jaime Lagos, Loredana Arata, Alejandra Acevedo, Winston Andrade, Gabriel Leal, Carolina Tambley, Patricia Bustos, Rodrigo Fasce, Jorge Fernández
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Public Health
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Online Access:https://www.frontiersin.org/article/10.3389/fpubh.2020.562615/full
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author Andrés E. Castillo
Bárbara Parra
Paz Tapia
Jaime Lagos
Loredana Arata
Alejandra Acevedo
Winston Andrade
Gabriel Leal
Carolina Tambley
Patricia Bustos
Rodrigo Fasce
Jorge Fernández
author_facet Andrés E. Castillo
Bárbara Parra
Paz Tapia
Jaime Lagos
Loredana Arata
Alejandra Acevedo
Winston Andrade
Gabriel Leal
Carolina Tambley
Patricia Bustos
Rodrigo Fasce
Jorge Fernández
author_sort Andrés E. Castillo
collection DOAJ
description The pandemic caused by the new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a worldwide public health concern. First confined in China and then disseminated widely across Europe and America, SARS-CoV-2 has impacted and moved the scientific community around the world to working in a fast and coordinated way to collect all possible information about this virus and generate new strategies and protocols to try to stop the infection. During March 2020, more than 16,000 full viral genomes have been shared in public databases that allow the construction of genetic landscapes for tracking and monitoring the viral advances over time and study the genomic variations present in geographic regions. In this work, we present the occurrence of genetic variants and lineages of SARS-CoV-2 in Chile during March to April 2020. Complete genome analysis of 141 viral samples from different regions of Chile revealed a predominance of variant D614G like in Europe and the USA and the major presence of lineage B.1. These findings could help take control measures due to the similarity of the viral variants present in Chile, compared with other countries, and monitor the dynamic change of virus variants in the country.
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spelling doaj.art-df77ab1637614175ab3f64a5914e25c32022-12-22T01:26:02ZengFrontiers Media S.A.Frontiers in Public Health2296-25652020-09-01810.3389/fpubh.2020.562615562615Geographical Distribution of Genetic Variants and Lineages of SARS-CoV-2 in ChileAndrés E. Castillo0Bárbara Parra1Paz Tapia2Jaime Lagos3Loredana Arata4Alejandra Acevedo5Winston Andrade6Gabriel Leal7Carolina Tambley8Patricia Bustos9Rodrigo Fasce10Jorge Fernández11Molecular Genetics Sub Department, Institute of Public Health of Chile, Santiago, ChileMolecular Genetics Sub Department, Institute of Public Health of Chile, Santiago, ChileMolecular Genetics Sub Department, Institute of Public Health of Chile, Santiago, ChileMolecular Genetics Sub Department, Institute of Public Health of Chile, Santiago, ChileMolecular Genetics Sub Department, Institute of Public Health of Chile, Santiago, ChileSection of Respiratory and Exanthematic Viruses, Institute of Public Health of Chile, Santiago, ChileSection of Respiratory and Exanthematic Viruses, Institute of Public Health of Chile, Santiago, ChileSection of Respiratory and Exanthematic Viruses, Institute of Public Health of Chile, Santiago, ChileSection of Respiratory and Exanthematic Viruses, Institute of Public Health of Chile, Santiago, ChileSection of Respiratory and Exanthematic Viruses, Institute of Public Health of Chile, Santiago, ChileSection of Respiratory and Exanthematic Viruses, Institute of Public Health of Chile, Santiago, ChileMolecular Genetics Sub Department, Institute of Public Health of Chile, Santiago, ChileThe pandemic caused by the new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a worldwide public health concern. First confined in China and then disseminated widely across Europe and America, SARS-CoV-2 has impacted and moved the scientific community around the world to working in a fast and coordinated way to collect all possible information about this virus and generate new strategies and protocols to try to stop the infection. During March 2020, more than 16,000 full viral genomes have been shared in public databases that allow the construction of genetic landscapes for tracking and monitoring the viral advances over time and study the genomic variations present in geographic regions. In this work, we present the occurrence of genetic variants and lineages of SARS-CoV-2 in Chile during March to April 2020. Complete genome analysis of 141 viral samples from different regions of Chile revealed a predominance of variant D614G like in Europe and the USA and the major presence of lineage B.1. These findings could help take control measures due to the similarity of the viral variants present in Chile, compared with other countries, and monitor the dynamic change of virus variants in the country.https://www.frontiersin.org/article/10.3389/fpubh.2020.562615/fullCOVID-19SARS-CoV- 2epidemiologyvariantslineages
spellingShingle Andrés E. Castillo
Bárbara Parra
Paz Tapia
Jaime Lagos
Loredana Arata
Alejandra Acevedo
Winston Andrade
Gabriel Leal
Carolina Tambley
Patricia Bustos
Rodrigo Fasce
Jorge Fernández
Geographical Distribution of Genetic Variants and Lineages of SARS-CoV-2 in Chile
Frontiers in Public Health
COVID-19
SARS-CoV- 2
epidemiology
variants
lineages
title Geographical Distribution of Genetic Variants and Lineages of SARS-CoV-2 in Chile
title_full Geographical Distribution of Genetic Variants and Lineages of SARS-CoV-2 in Chile
title_fullStr Geographical Distribution of Genetic Variants and Lineages of SARS-CoV-2 in Chile
title_full_unstemmed Geographical Distribution of Genetic Variants and Lineages of SARS-CoV-2 in Chile
title_short Geographical Distribution of Genetic Variants and Lineages of SARS-CoV-2 in Chile
title_sort geographical distribution of genetic variants and lineages of sars cov 2 in chile
topic COVID-19
SARS-CoV- 2
epidemiology
variants
lineages
url https://www.frontiersin.org/article/10.3389/fpubh.2020.562615/full
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