Non-Assembled ORF2 Capsid Protein of Porcine Circovirus 2b Does Not Confer Protective Immunity

Non-Assembled ORF2 Capsid Protein of Porcine Circovirus 2b Does Not Confer Protective Immunity

Porcine Circovirus 2 (PCV2) vaccines are based on either inactivated whole virion, or recombinant ORF2 capsid protein assembled into Virus-like Particles (VLPs). No data are available about the immunizing properties of free, non-assembled capsid protein. To investigate this issue, ORF2 of a referenc...

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Bibliographic Details
Main Authors: Flavia Guarneri, Matteo Tonni, Giuseppe Sarli, Maria Beatrice Boniotti, Davide Lelli, Ilaria Barbieri, Giulia D’Annunzio, Giovanni Loris Alborali, Barbara Bacci, Massimo Amadori
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Pathogens
Subjects:
pig
Porcine Circovirus 2
ORF2 capsid protein
vaccine
protection
Online Access:https://www.mdpi.com/2076-0817/10/9/1161

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