Clinical and molecular characteristics of acute myeloid leukemia and the dismal prognosis of TP53 mutations in a real-world setting

Clinical and molecular characteristics of acute myeloid leukemia and the dismal prognosis of TP53 mutations in a real-world setting

ABSTRACTObjectives: This study aimed to evaluate the incidence and prognostic significance of common cytogenetic and molecular abnormalities in patients with TP53-mutated and non-TP53-mutated acute myeloid leukemia (AML).Methods: We retrospectively analyzed the clinical data of 326 patients with new...

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Bibliographic Details
Main Authors: Hong Liu, Yuye Shi, Shandong Tao, Yunjie Li, Chunling Wang, Liang Yu
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Hematology
Subjects:
Acute myeloid leukemia
molecular abnormality
next-generation gene sequencing
cytogenetic abnormality
prognosis
Online Access:https://www.tandfonline.com/doi/10.1080/16078454.2023.2223866

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