Characterizations and Assays of α-Glucosidase Inhibition Activity on Gallic Acid Cocrystals: Can the Cocrystals be Defined as a New Chemical Entity During Binding with the α-Glucosidase?

Cocrystallization with co-former (CCF) has proved to be a powerful approach to improve the solubility and even bioavailability of poorly water-soluble active pharmaceutical ingredients (APIs). However, it is still uncertain whether a cocrystal would exert the pharmacological activity in the form of...

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Hlavní autoři: Na Xue, Yutao Jia, Congwei Li, Binnan He, Caiqin Yang, Jing Wang
Médium: Článek
Jazyk:English
Vydáno: MDPI AG 2020-03-01
Edice:Molecules
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On-line přístup:https://www.mdpi.com/1420-3049/25/5/1163