The Impact of the Recurrent Laryngeal Nerve Injury on Prognosis After McKeown Esophagectomy for ESCC
Rirong Qu, Dehao Tu, Wei Ping, Xiangning Fu Department of Thoracic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, People’s Republic of ChinaCorrespondence: Xiangning FuDepartment of Thoracic Surgery, Tongji Hospital, Tongji M...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2021-02-01
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| Series: | Cancer Management and Research |
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| Online Access: | https://www.dovepress.com/the-impact-of-the-recurrent-laryngeal-nerve-injury-on-prognosis-after--peer-reviewed-article-CMAR |
| _version_ | 1818410231063904256 |
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| author | Qu R Tu D Ping W Fu X |
| author_facet | Qu R Tu D Ping W Fu X |
| author_sort | Qu R |
| collection | DOAJ |
| description | Rirong Qu, Dehao Tu, Wei Ping, Xiangning Fu Department of Thoracic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, People’s Republic of ChinaCorrespondence: Xiangning FuDepartment of Thoracic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, People’s Republic of ChinaTel +86 13607150390Fax +86 027-83665211Email fuxn2006@aliyun.comBackground: The objective of this study was to assess the impact of the recurrent laryngeal nerve injury (RLNI) after esophagectomy on prognosis.Methods: Retrospectively collected data from 297 patients with esophageal squamous cell carcinoma (ESCC) who underwent McKeown esophagectomy at our department from April 2014 to May 2018, were analyzed.Results: RLNI occurred in 31.9% of the patients. Left-side RLNI occurred 2.8 times more often than right-side RLNI. Among the cases in which assessment of the vocal cords was continued, 8.4% involved permanent injury. There were no significant differences among clinicopathological data between patients with RLNI and without. Compared with patients without RLNI, patients with RNLI have longer operation time, more number of bronchoscopy suctions, longer postoperation hospital stay, and higher incidence of postoperative complications. T stage, N stage, RLN lymph node metastasis were independent risk factors for the prognosis, but RLNI is not independent risk factors for long-term survival.Conclusion: RLNI is a serious complication that will affect the short-term prognosis of patients and reduce the quality of life of patients. It should be avoided as much as possible during surgery, but it may not have negative impact on the long-term survival.Keywords: esophageal cancer, recurrent laryngeal nerve, injury, esophagectomy, prognosis |
| first_indexed | 2024-12-14T10:12:14Z |
| format | Article |
| id | doaj.art-df7ff43c8de741cda28d853fcab8b0b1 |
| institution | Directory Open Access Journal |
| issn | 1179-1322 |
| language | English |
| last_indexed | 2024-12-14T10:12:14Z |
| publishDate | 2021-02-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Cancer Management and Research |
| spelling | doaj.art-df7ff43c8de741cda28d853fcab8b0b12022-12-21T23:06:59ZengDove Medical PressCancer Management and Research1179-13222021-02-01Volume 131861186862448The Impact of the Recurrent Laryngeal Nerve Injury on Prognosis After McKeown Esophagectomy for ESCCQu RTu DPing WFu XRirong Qu, Dehao Tu, Wei Ping, Xiangning Fu Department of Thoracic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, People’s Republic of ChinaCorrespondence: Xiangning FuDepartment of Thoracic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, People’s Republic of ChinaTel +86 13607150390Fax +86 027-83665211Email fuxn2006@aliyun.comBackground: The objective of this study was to assess the impact of the recurrent laryngeal nerve injury (RLNI) after esophagectomy on prognosis.Methods: Retrospectively collected data from 297 patients with esophageal squamous cell carcinoma (ESCC) who underwent McKeown esophagectomy at our department from April 2014 to May 2018, were analyzed.Results: RLNI occurred in 31.9% of the patients. Left-side RLNI occurred 2.8 times more often than right-side RLNI. Among the cases in which assessment of the vocal cords was continued, 8.4% involved permanent injury. There were no significant differences among clinicopathological data between patients with RLNI and without. Compared with patients without RLNI, patients with RNLI have longer operation time, more number of bronchoscopy suctions, longer postoperation hospital stay, and higher incidence of postoperative complications. T stage, N stage, RLN lymph node metastasis were independent risk factors for the prognosis, but RLNI is not independent risk factors for long-term survival.Conclusion: RLNI is a serious complication that will affect the short-term prognosis of patients and reduce the quality of life of patients. It should be avoided as much as possible during surgery, but it may not have negative impact on the long-term survival.Keywords: esophageal cancer, recurrent laryngeal nerve, injury, esophagectomy, prognosishttps://www.dovepress.com/the-impact-of-the-recurrent-laryngeal-nerve-injury-on-prognosis-after--peer-reviewed-article-CMAResophageal cancerrecurrent laryngeal nerveinjuryesophagectomyprognosis |
| spellingShingle | Qu R Tu D Ping W Fu X The Impact of the Recurrent Laryngeal Nerve Injury on Prognosis After McKeown Esophagectomy for ESCC Cancer Management and Research esophageal cancer recurrent laryngeal nerve injury esophagectomy prognosis |
| title | The Impact of the Recurrent Laryngeal Nerve Injury on Prognosis After McKeown Esophagectomy for ESCC |
| title_full | The Impact of the Recurrent Laryngeal Nerve Injury on Prognosis After McKeown Esophagectomy for ESCC |
| title_fullStr | The Impact of the Recurrent Laryngeal Nerve Injury on Prognosis After McKeown Esophagectomy for ESCC |
| title_full_unstemmed | The Impact of the Recurrent Laryngeal Nerve Injury on Prognosis After McKeown Esophagectomy for ESCC |
| title_short | The Impact of the Recurrent Laryngeal Nerve Injury on Prognosis After McKeown Esophagectomy for ESCC |
| title_sort | impact of the recurrent laryngeal nerve injury on prognosis after mckeown esophagectomy for escc |
| topic | esophageal cancer recurrent laryngeal nerve injury esophagectomy prognosis |
| url | https://www.dovepress.com/the-impact-of-the-recurrent-laryngeal-nerve-injury-on-prognosis-after--peer-reviewed-article-CMAR |
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