A Novel Vitronectin Peptide Facilitates Differentiation of Oligodendrocytes from Human Pluripotent Stem Cells (Synthetic ECM for Oligodendrocyte Differentiation)

A Novel Vitronectin Peptide Facilitates Differentiation of Oligodendrocytes from Human Pluripotent Stem Cells (Synthetic ECM for Oligodendrocyte Differentiation)

Differentiation of oligodendrocytes (ODs) presents a challenge in regenerative medicine due to their role in various neurological diseases associated with dysmyelination and demyelination. Here, we designed a peptide derived from vitronectin (VN) using in silico docking simulation and examined its u...

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Bibliographic Details
Main Authors: Won Ung Park, Gyu-Bum Yeon, Myeong-Sang Yu, Hui-Gwan Goo, Su-Hee Hwang, Dokyun Na, Dae-Sung Kim
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Biology
Subjects:
oligodendrocytes
differentiation
hPSCs
vitronectin
transcriptomic analysis
Online Access:https://www.mdpi.com/2079-7737/10/12/1254

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