α<sub>2</sub>δ-4 and Cachd1 Proteins Are Regulators of Presynaptic Functions

α<sub>2</sub>δ-4 and Cachd1 Proteins Are Regulators of Presynaptic Functions

The α<sub>2</sub>δ auxiliary subunits of voltage-gated calcium channels (VGCC) were traditionally regarded as modulators of biophysical channel properties. In recent years, channel-independent functions of these subunits, such as involvement in synapse formation, have been identified. In...

Full description

Bibliographic Details
Main Authors:	Cornelia Ablinger, Clarissa Eibl, Stefanie M. Geisler, Marta Campiglio, Gary J. Stephens, Markus Missler, Gerald J. Obermair
Format:	Article
Language:	English
Published:	MDPI AG 2022-08-01
Series:	International Journal of Molecular Sciences
Subjects:	α<sub>2</sub>δ subunits Cachd1 synapse formation synaptic differentiation presynaptic calcium imaging voltage-gated calcium channels
Online Access:	https://www.mdpi.com/1422-0067/23/17/9885

Similar Items

Presynaptic nanodomains: a tale of two synapses
by: Lu-Yang eWANG, et al.
Published: (2015-01-01)

Postsynaptic Neuroligin-1 Mediates Presynaptic Endocytosis During Neuronal Activity
by: Jiaqi Keith Luo, et al.
Published: (2021-10-01)

The Ever-Growing Puzzle of Asynchronous Release
by: Andrei Rozov, et al.
Published: (2019-02-01)

NMDA receptor-dependent presynaptic inhibition at the calyx of Held synapse of rat pups
by: Tomoko Oshima-Takago, et al.
Published: (2017-01-01)

Gabapentin Disrupts Binding of Perlecan to the α<sub>2</sub>δ<sub>1</sub> Voltage Sensitive Calcium Channel Subunit and Impairs Skeletal Mechanosensation
by: Perla C. Reyes Fernandez, et al.
Published: (2022-12-01)

Imaging and Analysis of Presynaptic Calcium Influx in Cultured Neurons Using synGCaMP6f
by: Johannes Brockhaus, et al.
Published: (2019-04-01)

Role of α2δ-3 in regulating calcium channel localization at presynaptic active zones during homeostatic plasticity
by: Yanfeng Zhang, et al.
Published: (2023-11-01)

On the Role of Glutamate in Presynaptic Development: Possible Contributions of Presynaptic NMDA Receptors
by: Karlie N. Fedder, et al.
Published: (2015-12-01)

Corrigendum: Role of α2δ-3 in regulating calcium channel localization at presynaptic active zones during homeostatic plasticity
by: Yanfeng Zhang, et al.
Published: (2023-12-01)

Presynaptic Boutons That Contain Mitochondria Are More Stable
by: Robert M. Lees, et al.
Published: (2020-01-01)

Mechanistic insights into neurotransmitter release and presynaptic plasticity from the crystal structure of Munc13-1 C1C2BMUN
by: Junjie Xu, et al.
Published: (2017-02-01)

Nanoscale dynamics of synaptic vesicle trafficking and fusion at the presynaptic active zone
by: Thirumalini Vaithianathan, et al.
Published: (2016-02-01)

Altered Synaptic Vesicle Release and Ca2+ Influx at Single Presynaptic Terminals of Cortical Neurons in a Knock-in Mouse Model of Huntington’s Disease
by: Sidong Chen, et al.
Published: (2018-12-01)

Synaptic spinules are reliable indicators of excitatory presynaptic bouton size and strength and are ubiquitous components of excitatory synapses in CA1 hippocampus
by: Ashley Gore, et al.
Published: (2022-08-01)

Release properties of individual presynaptic boutons expressed during homosynaptic depression and heterosynaptic facilitation of the Aplysia sensorimotor synapse
by: Guy eMalkinson, et al.
Published: (2013-09-01)

Presynaptic LRP4 promotes synapse number and function of excitatory CNS neurons
by: Timothy J Mosca, et al.
Published: (2017-06-01)

Presynaptic NMDA receptors facilitate short-term plasticity and BDNF release at hippocampal mossy fiber synapses
by: Pablo J Lituma, et al.
Published: (2021-06-01)

Regulation of presynaptic Ca2+ channel abundance at active zones through a balance of delivery and turnover
by: Karen L Cunningham, et al.
Published: (2022-07-01)

Acetylcholine-induced inhibition of presynaptic calcium signals and transmitter release in the frog neuromuscular junction
by: Eduard Khaziev, et al.
Published: (2016-12-01)

Estimation of presynaptic calcium currents and endogenous calcium buffers at the frog neuromuscular junction with two different calcium fluorescent dyes
by: Dmitry eSamigullin, et al.
Published: (2015-01-01)

Effect of Al<sub>2</sub>O<sub>3</sub> on Sintering Reaction of Calcium Ferrite
by: Zhenwei Jing, et al.
Published: (2022-08-01)

Altered exocytosis of inhibitory synaptic vesicles at single presynaptic terminals of cultured striatal neurons in a knock-in mouse model of Huntington’s disease
by: Chen Xu, et al.
Published: (2023-08-01)

Visualizing presynaptic calcium dynamics and vesicle fusion with a single genetically encoded reporter at individual synapses
by: Rachel E Jackson, et al.
Published: (2016-07-01)

Synaptic vesicle capture by CaV2.2 calcium channels
by: Fiona K. Wong, et al.
Published: (2013-06-01)

α2δ-3 Is Required for Rapid Transsynaptic Homeostatic Signaling
by: Tingting Wang, et al.
Published: (2016-09-01)

A Carbide Slag-Based, Ca<sub>12</sub>Al<sub>14</sub>O<sub>33</sub>-Stabilized Sorbent Prepared by the Hydrothermal Template Method Enabling Efficient CO<sub>2</sub> Capture
by: Xiaotong Ma, et al.
Published: (2019-07-01)

The α<sub>2</sub>δ Calcium Channel Subunit Accessorily and Independently Affects the Biological Function of <i>Ditylenchus destructor</i>
by: Xueling Chen, et al.
Published: (2022-10-01)

PTPδ is a presynaptic organizer for the formation and maintenance of climbing fiber to Purkinje cell synapses in the developing cerebellum
by: Yuto Okuno, et al.
Published: (2023-06-01)

Clarinet (CLA-1), a novel active zone protein required for synaptic vesicle clustering and release
by: Zhao Xuan, et al.
Published: (2017-11-01)

Methods of measuring presynaptic function with fluorescence probes
by: Yeseul Jang, et al.
Published: (2021-03-01)

Active presynaptic ribosomes in the mammalian brain, and altered transmitter release after protein synthesis inhibition
by: Matthew S Scarnati, et al.
Published: (2018-10-01)

MCTP is an ER-resident calcium sensor that stabilizes synaptic transmission and homeostatic plasticity
by: Özgür Genç, et al.
Published: (2017-05-01)

Molecular Characterization of an SV Capture Site in the Mid-Region of the Presynaptic CaV2.1 Calcium Channel C-Terminal
by: Christine A. Snidal, et al.
Published: (2018-05-01)

Adenosine A<sub>2A</sub> Receptors Shut Down Adenosine A<sub>1</sub> Receptor-Mediated Presynaptic Inhibition to Promote Implementation of Hippocampal Long-Term Potentiation
by: Cátia R. Lopes, et al.
Published: (2023-04-01)

Mechanistic insights into cAMP-mediated presynaptic potentiation at hippocampal mossy fiber synapses
by: Ryota Fukaya, et al.
Published: (2023-07-01)

Upregulated Ca<sup>2+</sup> Release from the Endoplasmic Reticulum Leads to Impaired Presynaptic Function in Familial Alzheimer’s Disease
by: Temitope Adeoye, et al.
Published: (2022-07-01)

Presynaptic NMDA receptors and spike timing-dependent long-term depression at cortical synapses
by: Antonio Rodriguez Moreno, et al.
Published: (2010-06-01)

Environmental Enrichment Enhances Ca<sub>v</sub> 2.1 Channel-Mediated Presynaptic Plasticity in Hypoxic–Ischemic Encephalopathy
by: Suk-Young Song, et al.
Published: (2021-03-01)

Designing Composite BaCe<sub>0.4</sub>Zr<sub>0.4</sub>Y<sub>0.1</sub>Yb<sub>0.1</sub>O<sub>3-δ</sub>-Sm<sub>0.2</sub>Ce<sub>0.8</sub>O<sub>2-δ</sub> Heterostructure Electrolyte for Low-Temperature Ceramic Fuel Cell (LT-CFCs)
by: Wei Wei, et al.
Published: (2022-12-01)

MoS<sub>2</sub>-Based Memristor: Robust Resistive Switching Behavior and Reliable Biological Synapse Emulation
by: Yongfa Ling, et al.
Published: (2023-12-01)