Chemokine Ligand 2 Promotes Migration in Osteosarcoma by Regulating the miR-3659/MMP-3 Axis

Chemokine Ligand 2 Promotes Migration in Osteosarcoma by Regulating the miR-3659/MMP-3 Axis

Osteosarcoma is a common malignant tumor in children and adolescents, known for its aggressive invasion and distant metastasis, leading to a poor prognosis. Matrix metalloproteinases (MMPs) can degrade the extracellular matrix and basement membranes through their proteolytic activity, thereby promot...

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Bibliographic Details
Main Authors: Yu-Hsiang Chang, Yuan-Li Huang, Hsiao-Chi Tsai, An-Chen Chang, Chih-Yuan Ko, Yi-Chin Fong, Chih-Hsin Tang
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Biomedicines
Subjects:
osteosarcoma
CCL2
MMP-3
metastasis
miR-3659
Online Access:https://www.mdpi.com/2227-9059/11/10/2768

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