Conjugation of Gentamicin to Polyamidoamine Dendrimers Improved Anti-bacterial Properties against Pseudomonas aeruginosa

Conjugation of Gentamicin to Polyamidoamine Dendrimers Improved Anti-bacterial Properties against Pseudomonas aeruginosa

Purpose: This study aimed to design gentamicin-conjugated poly (amidoamine) (PAMAM) dendrimers to increase the therapeutic efficiency of gentamicin against Pseudomonas aeruginosa. Methods: Gentamicin-presenting dendrimers were synthesized using MAL-PEG3400-NHS as a redox-sensitive linker to attach g...

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Bibliographic Details
Main Authors: Hamed Sheykhloo, Morteza Milani, Farhood Najafi, Farhad Bani, Amir Zarebkohan
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2021-09-01
Series:Advanced Pharmaceutical Bulletin
Subjects:
gentamicin
pamam dendrimers
pseudomonas aeruginosa
drug delivery
anti-bacterial capacity
Online Access:https://apb.tbzmed.ac.ir/PDF/apb-11-675.pdf

Internet

https://apb.tbzmed.ac.ir/PDF/apb-11-675.pdf

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