In vitro evaluation for estrogenic mechanisms of the disinfectant benzalkonium chloride as an emerging contaminant

In vitro evaluation for estrogenic mechanisms of the disinfectant benzalkonium chloride as an emerging contaminant

This study aimed to evaluate in vitro the possible mechanisms underlying the estrogenic potential of benzalkonium chloride (BAC) as a disinfectant emerging contaminant. Effects of BAC at the environmentally-relevant concentrations on estrogen synthesis and estrogen receptor (ER) signaling were asses...

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Bibliographic Details
Main Authors: Songyi Wei, Xianmin Hu, Xinyi Hu, Yisheng Wan, Guangquan Fan, Jun Wang
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2023-07-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Benzalkonium chloride
Disinfectant emerging contaminant
Estrogenic mechanisms
Xenoestrogen
Human adrenal H295R cell line
Estrogen receptor positive MCF-7 cell line
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2023000100650&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2023000100650&tlng=en

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