Sex differences in PTSD risk: evidence from post-conflict populations challenges the general assumption of increased vulnerability in females

Background: Next to the dose-dependent effect of trauma load, female sex represents a well-established risk factor for PTSD. Exposure to particularly toxic traumatic event types, different coping styles, and biological risk factors are frequently listed as potential causes for the increased PTSD vul...

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Main Authors: Sarah Wilker, Stephan Kolassa, Hawkar Ibrahim, Vathsalan Rajan, Anett Pfeiffer, Claudia Catani, Iris-Tatjana Kolassa
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:European Journal of Psychotraumatology
Subjects:
Online Access:http://dx.doi.org/10.1080/20008198.2021.1930702
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author Sarah Wilker
Stephan Kolassa
Hawkar Ibrahim
Vathsalan Rajan
Anett Pfeiffer
Claudia Catani
Iris-Tatjana Kolassa
author_facet Sarah Wilker
Stephan Kolassa
Hawkar Ibrahim
Vathsalan Rajan
Anett Pfeiffer
Claudia Catani
Iris-Tatjana Kolassa
author_sort Sarah Wilker
collection DOAJ
description Background: Next to the dose-dependent effect of trauma load, female sex represents a well-established risk factor for PTSD. Exposure to particularly toxic traumatic event types, different coping styles, and biological risk factors are frequently listed as potential causes for the increased PTSD vulnerability in females. Nevertheless, sex differences have not been consistently observed in all study populations. Objective: To investigate sex differences in PTSD risk in post-conflict populations from different countries while considering trauma load. Method: In civilian post-conflict samples from Northern Uganda (N = 1665), Rwanda (N = 433), Syria (N = 974) and Sri Lanka (N = 165), we investigated sex differences in PTSD risk while taking trauma load into account. PTSD and trauma load were assessed using standardized diagnostic interviews. Potential sex differences in PTSD risk were analysed by logistic regression analyses considering trauma load. Results: Across all samples, males reported more traumatic events than females. Both sexes predominantly reported war-related traumatic events. Without considering trauma load, sex effects in PTSD risk were only detected in the Syrian sample. When taking trauma load into account, evidence for an increased PTSD vulnerability in females was found in the Syrian sample, and, to a much lesser extent, in the Northern Ugandan sample. Conclusion: In contrast to the literature, we did not find evidence for a general increased PTSD vulnerability in females. The dose-response effect of trauma load was a much stronger predictor of PTSD risk than sex across all samples.
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spelling doaj.art-df84b9afae37414ebf2c7759b54b06462023-04-18T14:59:10ZengTaylor & Francis GroupEuropean Journal of Psychotraumatology2000-80662021-01-0112110.1080/20008198.2021.19307021930702Sex differences in PTSD risk: evidence from post-conflict populations challenges the general assumption of increased vulnerability in femalesSarah Wilker0Stephan Kolassa1Hawkar Ibrahim2Vathsalan Rajan3Anett Pfeiffer4Claudia Catani5Iris-Tatjana Kolassa6Bielefeld UniversitySAP Switzerland AGBielefeld UniversityBielefeld Universityvivo International e.VBielefeld Universityvivo International e.VBackground: Next to the dose-dependent effect of trauma load, female sex represents a well-established risk factor for PTSD. Exposure to particularly toxic traumatic event types, different coping styles, and biological risk factors are frequently listed as potential causes for the increased PTSD vulnerability in females. Nevertheless, sex differences have not been consistently observed in all study populations. Objective: To investigate sex differences in PTSD risk in post-conflict populations from different countries while considering trauma load. Method: In civilian post-conflict samples from Northern Uganda (N = 1665), Rwanda (N = 433), Syria (N = 974) and Sri Lanka (N = 165), we investigated sex differences in PTSD risk while taking trauma load into account. PTSD and trauma load were assessed using standardized diagnostic interviews. Potential sex differences in PTSD risk were analysed by logistic regression analyses considering trauma load. Results: Across all samples, males reported more traumatic events than females. Both sexes predominantly reported war-related traumatic events. Without considering trauma load, sex effects in PTSD risk were only detected in the Syrian sample. When taking trauma load into account, evidence for an increased PTSD vulnerability in females was found in the Syrian sample, and, to a much lesser extent, in the Northern Ugandan sample. Conclusion: In contrast to the literature, we did not find evidence for a general increased PTSD vulnerability in females. The dose-response effect of trauma load was a much stronger predictor of PTSD risk than sex across all samples.http://dx.doi.org/10.1080/20008198.2021.1930702posttraumatic stress disorderprevalencesex differencestrauma loadconflictwar
spellingShingle Sarah Wilker
Stephan Kolassa
Hawkar Ibrahim
Vathsalan Rajan
Anett Pfeiffer
Claudia Catani
Iris-Tatjana Kolassa
Sex differences in PTSD risk: evidence from post-conflict populations challenges the general assumption of increased vulnerability in females
European Journal of Psychotraumatology
posttraumatic stress disorder
prevalence
sex differences
trauma load
conflict
war
title Sex differences in PTSD risk: evidence from post-conflict populations challenges the general assumption of increased vulnerability in females
title_full Sex differences in PTSD risk: evidence from post-conflict populations challenges the general assumption of increased vulnerability in females
title_fullStr Sex differences in PTSD risk: evidence from post-conflict populations challenges the general assumption of increased vulnerability in females
title_full_unstemmed Sex differences in PTSD risk: evidence from post-conflict populations challenges the general assumption of increased vulnerability in females
title_short Sex differences in PTSD risk: evidence from post-conflict populations challenges the general assumption of increased vulnerability in females
title_sort sex differences in ptsd risk evidence from post conflict populations challenges the general assumption of increased vulnerability in females
topic posttraumatic stress disorder
prevalence
sex differences
trauma load
conflict
war
url http://dx.doi.org/10.1080/20008198.2021.1930702
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