Patulin induces ROS-dependent cardiac cell toxicity by inducing DNA damage and activating endoplasmic reticulum stress apoptotic pathway

Patulin induces ROS-dependent cardiac cell toxicity by inducing DNA damage and activating endoplasmic reticulum stress apoptotic pathway

Patulin (PAT) is one of the mycotoxins commonly found in agricultural products and fruits, and has obvious toxic effects on animals and humans. PAT has been found to cause myocardial toxicity and oxidative damage, but the mechanism of myocardial toxicity remained to be elucidated. We investigated th...

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Bibliographic Details
Main Authors: Baigang Zhang, Chenghui Huang, Dongmei Xu, Ke Huang, Yang Li, Lu Jiao, Binggang Fu, Subing Li, Yi Li
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Patulin
Cycle arrest
DNA damage
Endoplasmic reticulum stress
Apoptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651323012885

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